Gelatin Sponge Application

Gelatin sponge application is the use of a porous, biodegradable gelatin matrix to absorb fluids, support biological materials, or promote localized tissue responses. Its interconnected pores take up blood or other liquids, concentrating clotting components and providing a physical framework that helps stabilize a developing clot or retain cells and compounds at a target site. In biology, gelatin sponges are used for hemostasis, wound management, tissue engineering, and localized drug delivery. Their absorbency, biocompatibility, and enzymatic breakdown make them useful for studying tissue repair and designing temporary scaffolds for regenerative applications.

Gelatin Sponge Application - Related Videos

Research

JoVE Journal - Medicine
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The Polyvinyl Alcohol Sponge Model Implantation

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Cited by 20 •

2012

A useful tool to analyze the effects of drugs, growth factors, and/or manipulated cells in an animal model of wound repair is described. This technique utilizes the properties of a polyvinyl alcohol (PVA) sponge to deliver and contain the desired treatment and also provide a platform to be excised and analyzed.

Research

JoVE Journal - Bioengineering

Alternating Magnetic Field-Responsive Hybrid Gelatin Microgels for Controlled Drug Release

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Cited by 10 •

2016

We present a facile method to fabricate a biodegradable gelatin-based drug release platform that is magneto-thermally responsive. This was achieved by incorporating superparamagnetic iron oxide nanoparticles and poly(N-isopropylacrylamide-co-acrylamide) within a spherical gelatin micro-network crosslinked by genipin, in conjunction with an alternating magnetic field application system.

A Novel Culture Model for Human Pluripotent Stem Cell Propagation on Gelatin in Placenta-conditioned Media

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Cited by 5 •

2015

This protocol provides a simple and efficient way to propagate human pluripotent stem cells (hPSCs) using only conditioned media derived from the human placenta in a gelatin-coated dish without additional exogenous supplementation or hPSC-specific synthetic substrata.

Fabrication and Surgical Application of Enriched Photo-crosslinked Gelatin–Riboflavin Hydrogels for Corneal Wound Repair in Rabbits

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2026

A reproducible protocol is presented for the preparation, enrichment, and application of an in situ blue‑light–crosslinkable gelatin–riboflavin hydrogel for corneal stromal wound repair in rabbits, including procedural steps for surgical handling, partial tarsorrhaphy, and postoperative care.

Zinc-Sponge Battery Electrodes that Suppress Dendrites

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Cited by 7 •

2020

The goal of the reported protocols is to create rechargeable zinc-sponge electrodes that suppress dendrites and shape change in zinc batteries, such as nickel–zinc or zinc–air.

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