Gold-coated Capillaries
Gold-coated Capillaries - Related Videos
05:02
Growth of Gold Dendritic Nanoforests on Titanium Nitride-coated Silicon Substrates
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Cited by 5 •
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This study presents a feasible procedure for synthesizing gold dendritic nanoforests on titanium nitride/silicon substrates. The thickness of gold dendritic nanoforests increases linearly within 15 min of a synthesis reaction.
11:20
Fabrication and Visualization of Capillary Bridges in Slit Pore Geometry
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Cited by 4 •
2014
A procedure for creating and imaging capillary bridges in slit-pore geometry is presented. The creation of capillary bridges relies on the formation of pillars to provide a directional physical and chemical heterogeneity to pin the fluid. Capillary bridges are formed and manipulated using microstages and visualized using a CCD camera.
14:53
Capillary Electrophoresis Separation of Monoclonal Antibody Isoforms Using a Neutral Capillary
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Cited by 2 •
2017
Here, we present a comprehensive capillary zone electrophoresis protocol for the assessment of intrinsic physicochemical heterogeneity of monoclonal antibodies as a quality attribute.
08:50
Capillary Electrophoresis (CE)
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2023
Source: Laboratory of Dr. B. Jill Venton - University of Virginia Capillary electrophoresis (CE) is a separation technique that separates molecules in an electric field according to size and charge. CE is performed in a small glass tube called a capillary that is filled with an electrolyte solution. Analytes are separated due to differences in electrophoretic mobility, which varies with charge, solvent viscosity, and size. Traditional electrophoresis in gels is limited in the amount of voltage...
10:38
Synthesis of Functionalized 10-nm Polymer-coated Gold Particles for Endothelium Targeting and Drug Delivery
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Cited by 8 •
2018
We describe a method of synthesizing biocompatible 10-nm gold nanoparticles, functionalized by coating poly-ethylene glycol onto the surface. These particles can be used in vitro and in vivo for delivering therapeutics to nanoscale cellular and extracellular spaces that are difficult to access with conventional nanoparticle sizes.
FAQs
The gold coating provides a conductive, chemically modifiable surface rather than serving only as a protective covering. Its conductivity can support electrochemical reactions, while the interface can be adjusted to influence interactions with material in the capillary. These combined properties allow measurements to reflect both electrical behavior and surface chemistry during biological analysis.
The narrow dimensions confine samples and control their movement within a small space. This supports localized measurements while reducing the amount of reagent required for an analysis. Such control is useful when working with biomolecules, cells, or other biological samples whose behavior or detection depends on conditions at a defined microscale interface.
Surface chemistry determines how the capillary interface can be modified and how biological material may interact with it, while electrical properties enable charge-related control and electrochemical reactions. Because both features operate at the sample interface, they can influence detection in localized measurements and help connect the observed signal with the properties of the biological sample.
In electrophoretic workflows, the capillary provides a confined pathway for the small-volume sample and helps control its movement. The gold surface contributes an electrically active, modifiable interface that can support the analytical environment. This combination makes the format suitable for separating biological materials while limiting reagent consumption and maintaining localized handling.
For electrochemical sensing, the gold layer supplies a conductive surface that can support electrochemical reactions near the confined sample. The capillary geometry keeps the measurement localized, and the modifiable interface can be adapted to the chemical context of the analysis. These features support detection workflows involving biomolecules, cells, and other biological samples.
They are useful when a workflow requires controlled movement of a small biological sample through a narrow space. Their capillary structure limits the sample volume and supports localized handling, while the gold coating adds electrical and chemical functionality. Researchers can therefore combine fluid control with surface-based or charge-related effects in microscale analytical procedures.