Graphene Support Films

Graphene support films are ultrathin graphene layers used to stabilize biological specimens during microscopy and related analyses, combining mechanical strength with minimal material thickness. Their atomically thin, conductive lattice provides a rigid, low-scattering substrate that can improve specimen adsorption, limit charging, and reduce movement under an electron beam; surface treatments can also adjust wettability and molecular interactions. In biology, these films support the preparation and imaging of proteins, viruses, membranes, and cellular structures by transmission electron microscopy and cryo-electron microscopy. They can improve specimen distribution and image quality while reducing the amount of sample required, supporting higher-resolution structural studies.

Graphene Support Films - Related Videos

Research

JoVE Journal - Biochemistry
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Preparation of Sample Support Films in Transmission Electron Microscopy using a Support Floatation Block

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Cited by 10 •

2021

Sample preparation for cryo-electron microscopy (cryo-EM) is a significant bottleneck in the structure determination workflow of this method. Here, we provide detailed methods for using an easy-to-use, three-dimensionally printed block for the preparation of support films to stabilize samples for transmission EM studies.

Research

JoVE Journal - Engineering

Synthesis and Functionalization of 3D Nano-graphene Materials: Graphene Aerogels and Graphene Macro Assemblies

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Cited by 5 •

2015

This video method describes the synthesis of high surface area, monolithic 3D graphene-based materials derived from polymer precursors as well as single layer graphene oxide.

Iridium Oxide-reduced Graphene Oxide Nanohybrid Thin Film Modified Screen-printed Electrodes as Disposable Electrochemical Paper Microfluidic pH Sensors

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Cited by 5 •

2016

The study demonstrates the growth of iridium oxide-reduced graphene oxide (IrO2-RGO) nanohybrid thin films on irregular and rough screen-printed carbon substrate through a green electrochemical synthesis, and their implementation as a pH sensor with a patterned paper-fluidic platform.

Graphene Coatings for Biomedical Implants

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Cited by 37 •

2013

Graphene offers potential as a coating material for biomedical implants. In this study we demonstrate a method for coating nitinol alloys with nanometer thick layers of graphene and determine how graphene may influence implant response.

Preparation of ZnO Nanorod/Graphene/ZnO Nanorod Epitaxial Double Heterostructure for Piezoelectrical Nanogenerator by Using Preheating Hydrothermal

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Cited by 4 •

2016

One-step fabrication method for obtaining freestanding epitaxial double heterostructure is presented. This approach could achieve ZnO coverage with a higher number density than that of the epitaxial single heterostructure, leading to a piezoelectric nanogenerator with an increased output electrical performance.

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