Human Chorionic Gonadotropin
Human Chorionic Gonadotropin - Related Videos
06:27
Chorion and Vitelline Membrane Mechanical Removal: A Method to Prepare Drosophila Oocytes for Direct Observation
0 Views •
2023
This video describes a method to mechanically remove the chorion and vitelline membranes from previously fixed mature Drosophila oocytes. The featured protocol shows a detailed demonstration of the procedure yielding oocytes compatible with fluorescent in situ hybridization assays.
09:30
Dual Somatic Recordings from Gonadotropin-Releasing Hormone (GnRH) Neurons Identified by Green Fluorescent Protein (GFP) in Hypothalamic Slices
0 Views •
Cited by 3 •
2010
Activity in neuronal systems often requires synchronous action potential discharges from neurons within a specific population. For example, pulses of gonadotropin-releasing hormone (GnRH) likely require coordinated activity between GnRH neurons. We present our methodological approach for reliably obtaining simultaneous electrophysiological recordings from the diffusely distributed GnRH neurons.
05:22
Ex vivo Culture of Human Placental Explants for the Study of Viral Transmission Across the Maternal-Fetal Interface
0 Views •
2025
This protocol describes the preparation of human placental tissue explants cultured at an air-liquid interface for the study of viral infections.
04:47
Obtaining Eggs from Xenopus laevis Females
0 Views •
Cited by 10 •
2008
The eggs of Xenopus laevis intact, lysed, and/or fractionated are useful for a wide variety of experiments. This protocol shows how to induce egg laying, collect and dejelly the eggs, and sort the eggs to remove any damaged eggs.
12:02
Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption
0 Views •
Cited by 35 •
2016
This manuscript presents a unique in vitro model of immunopurified human villous cytotrophoblast cells cultured under hypoxia/reoxygenation. This model is suitable to study the protective effects of promising treatments, such as melatonin, on pregnancy complications associated with increased oxidative stress and altered placental function.
FAQs
hCG binds luteinizing hormone receptors on cells of the ovarian corpus luteum. This receptor interaction maintains progesterone production during the early stages of pregnancy, before the placenta can take over that hormonal role. The mechanism links placental trophoblast activity with continued ovarian support, helping preserve the hormonal conditions associated with early pregnancy.
Human chorionic gonadotropin shares functional similarity with luteinizing hormone because it can bind the same type of receptor on corpus luteum cells. That overlap allows a placental hormone to maintain progesterone production through an ovarian pathway normally influenced by luteinizing hormone. Its receptor activity therefore explains its importance during the transition from ovarian to placental support.
After entering maternal blood and urine, hCG can be measured outside the placental tissue where it is produced. Its concentration therefore provides an observable signal associated with early pregnancy. Measuring this signal supports pregnancy testing and allows hCG assays to contribute to monitoring early pregnancy rather than relying only on direct examination of placental cells.
Pregnancy tests use the presence of hCG in maternal urine or blood as an indicator of pregnancy. Because the hormone is released into these accessible body fluids, testing can detect a placental signal without sampling placental tissue. The measurable concentration also makes hCG relevant to monitoring early pregnancy, not only to an initial test result.
In biology and medicine, hCG assays support fertility treatment protocols by providing measurements of this pregnancy-associated hormone. The source material does not specify a particular treatment schedule or dosage, but it establishes that laboratory assessment of hCG has a role in fertility care. Its use illustrates how hormone measurements can inform reproductive medicine.
hCG assays can help evaluate certain placental tumors and germ-cell tumors because these conditions are included among the medical contexts in which hCG measurement is useful. The assay provides a measurable hormonal marker for assessment, although the source does not specify tumor types, diagnostic thresholds, or how results should be interpreted independently of other clinical information.