Infusion Pump Calibration
Infusion Pump Calibration - Related Videos
04:21
Controlled Infusion of Radiopharmaceutical Agent Using a Peristaltic Pump
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2025
Source: Léa Rubira1, Hélène Sturer1, Louise Combette1, Sandra Santini1, Stéphane Renaud1, Cyril Fersing1,21Nuclear medicine department, Institut régional du Cancer de Montpellier (ICM), Univ Montpellier, 2IBMM, Univ Montpellier, CNRS, ENSCMThis video demonstrates the safe, controlled infusion of a radiopharmaceutical using a peristaltic pump with a dual-line cassette system. The setup includes connecting saline and infusion lines, positioning the shielded vial, and initiating simultaneous...
10:19
Neurodegeneration in an Animal Model of Chronic Amyloid-beta Oligomer Infusion Is Counteracted by Antibody Treatment Infused with Osmotic Pumps
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Cited by 11 •
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To study the effects of Aβo in vivo, we developed a model based on repeated hippocampal infusions of soluble Aβo coupled with continuous infusion of Aβo antibody (6E10) in the hippocampus using osmotic pumps to counteract the neurotoxic effect of Aβo.
07:21
Subcutaneous Angiotensin II Infusion using Osmotic Pumps Induces Aortic Aneurysms in Mice
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Cited by 84 •
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Subcutaneous implantation of osmotic pumps provides a convenient approach for prolonged and consistent delivery of compounds. This approach has been used extensively to study both abdominal and thoracic aortic aneurysms in mice.
04:31
Continuous Drug Infusion System in Mouse Model: A Surgical Procedure to Implant Micro-osmotic Pump Infusion System in the Mouse Brain for Continuous Drug Delivery
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2025
In this video, we demonstrate the assembly of a micro-osmotic pump brain infusion system followed by its surgical implantation in the mouse skull. This system enables continuous delivery of potential drugs and facilitates the study of their effects on the brain and brain tissue.
08:32
Preparing and Administering Intermittent Intravenous Medications with an Infusion Pump
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2017
Source: Madeline Lassche, MSNEd, RN and Katie Baraki, MSN, RN, College of Nursing, University of Utah, UT Primary intermittent intravenous (IV) infusions are delivered alone as volume-controlled infusions, while secondary infusions are delivered with another IV fluid, usually maintenance fluids. Intermittent infusions are delivered over a specific amount of time, which is dictated by the type of medication, such as IV antibiotics. High-volume IV medications, anywhere from 50- to 500-mL...
FAQs
A calibration check compares the pump’s programmed delivery with fluid collected over a defined period. The collected amount is determined by mass or volume and then compared with the expected output. A mismatch indicates that the programmed setting does not represent the actual delivery rate, allowing the pump to be adjusted before experimental use.
Tubing characteristics, syringe dimensions, occlusion, and changing operating conditions can all affect the delivered amount. These influences may cause the measured output to differ from the programmed setting even when the pump appears to operate normally. Checking these factors helps distinguish a calibration problem from an error introduced by the fluid pathway or experimental conditions.
Controlled conditions make the comparison between programmed and measured delivery more reproducible. If operating conditions change during testing, the resulting difference may reflect the environment or fluid pathway rather than the pump setting itself. Consistent calibration conditions therefore improve confidence that later biological results reflect the intended treatment or nutrient delivery.
Set the pump to the intended delivery parameters, collect its output for a defined period, and determine the collected fluid’s mass or volume. Compare that measurement with the programmed output, then adjust the pump when the values do not agree. Repeating the check under controlled conditions helps verify that the corrected setting provides the expected delivery.
Calibration is particularly useful when a study depends on accurate, reproducible delivery of culture media, drugs, nutrients, or other solutions. It supports controlled conditions in cell culture, animal studies, and laboratory models. Verifying delivery before an experiment can reduce uncertainty about whether observed biological effects result from the intended solution exposure.
Calibration results provide evidence about whether the administered fluid amount matched the experimental design. If delivery is inaccurate, differences in culture conditions, drug exposure, or nutrient supply may complicate interpretation. Identifying and correcting flow-rate errors strengthens experimental control, making comparisons between samples, treatments, or biological models more meaningful.