Knee Joint

The knee joint is a synovial hinge joint that connects the femur, tibia, and patella, enabling the leg to bend, extend, and support body weight. Its smooth articular cartilage and synovial fluid reduce friction, while ligaments stabilize the bones and menisci distribute loads across the joint during movement. Surrounding muscles generate motion and help control forces during walking, running, and jumping. Studying knee joint structure and biomechanics supports understanding of normal locomotion, injury mechanisms, osteoarthritis, and rehabilitation, while informing approaches to diagnosis, treatment, prosthetic design, and tissue engineering.

Knee Joint - Related Videos

Education

JoVE Core - Anatomy and Physiology

Knee Joint

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2023

The knee joint is the most complicated joint in the body. It consists of three articulations– two tibiofemoral and one patellofemoral. As is characteristic of synovial joints, the knee joint has a thin articular capsule that partially surrounds this joint cavity. Additionally, several ligaments, muscles, and cartilaginous structures support the movement of the knee. A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris group...

Visualization of Knee Joint Degeneration after Non-invasive ACL Injury in Rats

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2023

Source: Lindsey K. Lepley1,2, Steven M. Davi1, Timothy A. Butterfield3,4 and Sina Shahbazmohamadi5, 1Department of Kinesiology, University of Connecticut, Storrs, CT; 2Department of Orthopaedic Surgery, University of Connecticut Health Center, Farmington, CT; 3Department of Rehabilitation Sciences, University of Kentucky, Lexington, KY; 4Center for Muscle Biology, Department of Physiology, University of Kentucky, Lexington, KY; 5Biomedical Engineering Department, University of Connecticut,...

Research

JoVE Journal - Biology

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint

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Cited by 12 •

2021

Primary tissues obtained from patients following total knee arthroplasty provide an experimental model for osteoarthritis research with maximal clinical translatability. This protocol describes how to identify, process, and isolate RNA from seven unique knee tissues to support mechanistic investigation in human osteoarthritis.

Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots

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Cited by 32 •

2013

An experimental technique for the treatment of osteochondral defects in the rabbit's knee joint is described. The implantation of allogeneic mesenchymal stem cells into osteochondral defects provides a promising development in the field of tissue engineering. The preparation of fibrin-cell-clots in vitro offers a standardized method for implantation.

Knee Exam

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2023

Source: Robert E. Sallis, MD. Kaiser Permanente, Fontana, California, USA The knee is a hinged joint that connects the femur with the tibia. It is the largest joint in the body, and due to its location in the middle of the lower leg, it is subjected to a variety of traumatic and degenerative forces. Examination of the knee can be quite complex, owing to the fact it is an inherently unstable joint held together by various ligaments and supported by menisci, which act as shock absorbers and...

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