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Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint
 

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint

Article DOI: 10.3791/62718-v
July 22nd, 2021

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Summary July 22nd, 2021

Primary tissues obtained from patients following total knee arthroplasty provide an experimental model for osteoarthritis research with maximal clinical translatability. This protocol describes how to identify, process, and isolate RNA from seven unique knee tissues to support mechanistic investigation in human osteoarthritis.

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