Licorice Flavonoids

Licorice flavonoids are polyphenolic secondary metabolites produced by Glycyrrhiza species, where they contribute to plant defense, pigmentation, and chemical diversity. Their hydroxylated aromatic structures enable redox activity and interactions with cellular proteins and membranes, while biosynthetic enzymes assemble distinct flavonoid compounds from phenylpropanoid-derived precursors. In biology, researchers examine these molecules to characterize plant metabolism, compare licorice species, and investigate antioxidant, antimicrobial, and anti-inflammatory activities in experimental systems. Their structural diversity also supports studies of plant adaptation and provides candidate molecules for pharmacological research, although biological effects depend on compound identity, concentration, and experimental conditions.

Licorice Flavonoids - Related Videos

Research

JoVE Journal - Chemistry

Flavonoid Content During the Growth and Floral Development of Calendula officinalis L.

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Cited by 1 •

2025

Here, we present the aluminum chloride colorimetric method, a direct analytical technique to determine flavonoids in calendula quantitatively. This approach utilizes a straightforward chemical reaction involving treating the calendula extract with an aluminum chloride reagent, forming a colored complex. The color intensity, assessed using spectrophotometry, correlates with the flavonoid concentration.

Synthesis of Plant Phenol-derived Polymeric Dyes for Direct or Mordant-based Hair Dyeing

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Cited by 12 •

2016

Here, we present a protocol to use pre-synthesized polymeric products derived from fungal laccase-catalyzed polymerization of plant phenols, either with or without mordant agents (e.g., FeSO4), to induce detergent-resistant keratin hair dyeing within 2.5 hours.

Extraction and Purification of Polyphenols from Freeze-dried Berry Powder for the Treatment of Vascular Smooth Muscle Cells In Vitro

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Cited by 9 •

2017

This work details a step-by-step method to prepare polyphenol-rich extracts from freeze-dried berry powder. In addition, it provides a thorough description of how to use these polyphenol-rich extracts in cell culture in the presence of the peptide hormone angiotensin II (Ang II) using Vascular Smooth Muscle Cells (VSMCs).

The Terroir Concept Interpreted through Grape Berry Metabolomics and Transcriptomics

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Cited by 10 •

2016

This article describes the application of untargeted metabolomics, transcriptomics and multivariate statistical analysis to grape berry transcripts and metabolites in order to gain insight into the terroir concept, i.e., the impact of the environment on berry quality traits.

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