Manual Examination

Manual examination is the direct inspection and assessment of biological specimens, structures, or organisms by a trained observer, often using the unaided eye or simple tools. It works through systematic observation, measurement, comparison with expected features, and careful recording of visible characteristics such as shape, color, size, texture, movement, or condition. In biology, manual examination supports specimen identification, anatomical study, preliminary diagnosis, and quality assessment before more specialized analysis. Although it can be influenced by observer experience and environmental conditions, it remains a practical, low-cost approach for teaching, fieldwork, routine laboratory assessment, and guiding the selection of follow-up methods.

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Education

JoVE Science Education - Basic Biology

Rabbit Handling and Manual Restraint

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2026

All animal procedures described here must be conducted in accordance with institutional animal ethics guidelines and approved by IACUC. All procedures must follow the principles of the 3Rs—Replacement, Reduction, and Refinement—and must be performed by trained personnel. Rabbits possess powerful hindlimb musculature and are susceptible to spinal injury if they struggle or kick while inadequately supported. Because rabbits vary in temperament and may struggle during restraint, handlers should...

Ophthalmoscopic Examination

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2023

Source: Richard Glickman-Simon, MD, Assistant Professor, Department of Public Health and Community Medicine, Tufts University School of Medicine, MA The simplest ophthalmoscopes consist of an aperture to look through, a diopter indicator, and a disc for selecting lenses. The ophthalmoscope is primarily used to examine the fundus, or the inner wall of the posterior eye, which consists of the choroid, retina, fovea, macula, optic disc, and retinal vessels (Figure 1). The spherical eyeball...

The Comprehensive Infant Examination

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2023

Source: Heather Collette and Jaideep Talwalkar; Yale School of Medicine The newborn exam is important in establishing a baby's baseline health status as they enter the world. Newborn providers have the unique opportunity to evaluate a patient for the very first time. They are also tasked with identifying congenital anomalies that require early intervention to promote a long and healthy life for the child. Many newborn anomalies, such as heart defects, are noted on prenatal ultrasound. However,...

Mental Status Examination

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2023

Source: Carmen Black, Matthew Goldenberg, and Jaideep Talwalkar; Yale School of Medicine The mental status exam is a clinical evaluation of emotional, perceptual, and cognitive functioning that spans both the fields of psychiatry and neurology. Developing skill in the psychiatric portions of the examination are important to describe salient aspects of the patient's mental state that may be observed during routine history and/or physical exam. Proficiency in the cognitive portions of this...

Research

JoVE Journal - Neuroscience
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Behavioral Assessment of Manual Dexterity in Non-Human Primates

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Cited by 45 •

2011

As manual dexterity is a prerogative mainly of primates, behavioral tasks have been developed in macaque monkeys. Four reach and grasp prehension tasks, measuring hand manipulation ability and force, allow to establish functional recovery after a lesion of the central nervous system and to test the effect of a treatment.

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