Disc Replacement Surgery

Disc replacement surgery is a spinal procedure that removes a damaged intervertebral disc and replaces it with an artificial implant, aiming to relieve pain while preserving movement between adjacent vertebrae. During the operation, surgeons access the affected spinal segment, excise degenerated disc material, and position a prosthetic disc designed to support load and permit controlled motion. The technique is used primarily for selected patients with symptomatic disc degeneration that has not improved with conservative care, although candidacy depends on spinal anatomy and other clinical factors. Studying it connects biology with vertebral biomechanics, tissue degeneration, implant design, and the evaluation of long-term function.

Disc Replacement Surgery - Related Videos

Research

JoVE Journal - Medicine

Automatic Surgery in Transcatheter Aortic Valve Replacement Using Augmented Reality

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Cited by 2 •

2024

This article presents the design and implementation of an automatic surgery module based on augmented reality (AR)- based 3D reconstruction. The system enables remote surgery by allowing surgeons to inspect reconstructed features and replicate surgical hand movements as if they were performing the surgery in close proximity.

Education

JoVE Science Education - Basic Biology

Considerations for Rodent Surgery

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2016

Source: Kay Stewart, RVT, RLATG, CMAR; Valerie A. Schroeder, RVT, RLATG. University of Notre Dame, IN The Guide for the Care and Use of Laboratory Animals1 dictates that rodent survival surgery be performed aseptically. Aseptic technique utilizes specific practices that minimize the contamination of the surgical site, including patient preparation, surgeon preparation, sterilization of instruments and other supplies, and the use of a clean and controlled environment. Presurgical planning,...

Research

JoVE Journal - Biology
Free Sample

Generation, Purification, and Characterization of Cell-invasive DISC1 Protein Species

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Cited by 13 •

2012

The generation, purification and cell invasion of intracellular, cytoplasmic full length DISC1 protein aggresomes from cell cultures and of a labeled, multimeric recombinant DISC1 protein fragment in E. coli are described. Cell invasiveness is shown for recipient cells in cell culture and for neurons in vivo after stereotactical brain inoculation.

Rodent Stereotaxic Surgery

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2023

Stereotaxic (or stereotactic) surgery is a method used to manipulate the brain of living animals. This technique allows researchers to accurately target deep structures within the brain through the use of a stereotaxic atlas, which provides the 3D coordinates of each area with respect to anatomical landmarks on the skull. After the skull is exposed, anesthetized animals are mounted on a specialized instrument known as a stereotaxic frame, which enables the precise placement of experimental...

Survivable Stereotaxic Surgery in Rodents

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Cited by 50 •

2008

The monitoring of extracellular neurotransmitter levels in distinct brain regions of freely moving animals offers insights on the link between neurotransmitter release and behavior. In vivo microdialysis coupled with electrochemical detection provides excellent anatomical and chemical resolution; and information on how basal neurotransmission is altered by pharmacological or physiological manipulations.

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