Muscle Function Evaluation

Muscle function evaluation is the systematic assessment of how muscles generate force, produce movement, and respond to physical demands, making it important for understanding normal biology and identifying functional impairment. Evaluators measure outcomes such as strength, endurance, range of motion, and coordination using physical examination, controlled movement tasks, or instruments that record force and electrical activity. In biology and health research, these assessments help relate muscle performance to cellular structure, motor control, exercise, aging, injury, and disease. Comparing measurements across conditions or over time can reveal treatment effects, guide rehabilitation, and clarify how muscles adapt to changes in workload.

Muscle Function Evaluation - Related Videos

Research

JoVE Journal - Biology
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Evaluation of Muscle Function of the Extensor Digitorum Longus Muscle Ex vivo and Tibialis Anterior Muscle In situ in Mice

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Cited by 75 •

2013

Changes in limb muscle contractile and passive mechanical properties are important biomarkers for muscle diseases. This manuscript describes physiological assays to measure these properties in the murine extensor digitorum longus and tibialis anterior muscles.

Applications of In Vivo Functional Testing of the Rat Tibialis Anterior for Evaluating Tissue Engineered Skeletal Muscle Repair

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Cited by 20 •

2016

We describe an in vivo protocol to measure dorsiflexion of the foot following stimulation of the peroneal nerve and contraction of the anterior crural compartment of the rat hindlimb. Such measurements are an indispensable translational tool for evaluating skeletal muscle pathology and tissue engineering approaches to muscle repair and regeneration.

Research

JoVE Journal - Medicine
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In Vivo Canine Muscle Function Assay

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Cited by 19 •

2011

We describe a minimally-invasive and painless method to measure canine hindlimb muscle strength and muscle response to repeated eccentric contractions.

Education

JoVE Core - Anatomy and Physiology

Functions of Smooth Muscles

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2024

Smooth muscles are an important type of muscle tissue that plays a vital role in the involuntary movements of internal organs. For example, they help regulate the movement of food through the gut and the flow of blood through the circulatory system. Function of visceral smooth muscles Visceral smooth muscle is found in the walls of all hollow organs, except the heart, and is a key player in the involuntary movements that drive the functioning of these internal organs. This tissue is arranged in...

Evaluation of Injury-induced Senescence and In Vivo Reprogramming in the Skeletal Muscle

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Cited by 14 •

2017

Here we present a detailed protocol to detect both senescent and pluripotent stem cells in the skeletal muscle upon injury while inducing in vivo reprogramming. This method is suitable for evaluating the role of cellular senescence during tissue regeneration and reprogramming in vivo.

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