Nasopharynx
Nasopharynx - Related Videos
09:12
Characterization of Inflammatory Responses During Intranasal Colonization with Streptococcus pneumoniae
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Cited by 27 •
2014
Colonization of the murine nasopharynx with Streptococcus pneumoniae and the subsequent extraction of adherent or recruited cells is described. This technique involves flushing the nasopharynx and collection of the fluid through the nares and is adaptable for various readouts, including differential cell quantification and analysis of mRNA expression in situ.
03:16
Processing of Infected Tissues for Bacterial Enumeration in a Mouse Co-Infection Model
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2026
Source: Lenhard, A., et al. A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness. J. Vis. Exp. (2022)This video demonstrates the processing of lungs from a mouse co-infected with a pathogenic bacterium and a virus. Mincing, homogenizing, and plating the lung tissue allows quantification of bacterial load, indicating bacterial spread to the lungs and disease severity.
04:46
A Novel Rescue Technique for Difficult Intubation and Difficult Ventilation
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2011
We describe a technique to maintain oxygenation and ventilation using an endotracheal tube inserted nasally to the level of the naso-pharynx while sealing the mouth and nares for successful positive pressure ventilation.
15:04
Modeling and Simulations of Olfactory Drug Delivery with Passive and Active Controls of Nasally Inhaled Pharmaceutical Aerosols
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Cited by 18 •
2016
This manuscript reviews the modeling and simulations of different protocols to deliver medications to the olfactory region in image-based nasal airway models. Multiple software modules are used to develop the anatomically accurate nose model, generate computational mesh, simulate nasal airflows, and predict particle deposition at the olfactory region.
05:50
Intranasal Delivery of mRNA Polyplexes via Rayleigh Breakup Aerosols: An In Vitro Method for Nasal Deposition and Functional Testing
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2026
This protocol presents Rayleigh breakup as a mild process for aerosolizing non-viral mRNA vectors. Regional deposition for aerosolized mRNA vectors is evaluated by the Alberta Idealized Nasal Inlet (AINI) model. Green fluorescence protein (GFP) expression in human lung cells represents maintenance of physicochemical and biological functions of post-aerosolized mRNA vectors.
FAQs
Mucus first traps particles carried in inhaled air, while cilia move the mucus and its captured material toward the throat. This coordinated transport helps clear the airway rather than leaving particles within the chamber. Studying both components explains how the nasopharynx contributes to respiratory protection through a physical removal process.
The auditory tube openings connect the nasopharyngeal region with the middle ears and support middle-ear ventilation. Their location makes the nasopharynx relevant beyond airflow through the respiratory tract. Examining this relationship helps explain how structures in one pharyngeal region can contribute to conditions in the ear through ventilation pathways.
The pharyngeal tonsil is lymphoid tissue located in the nasopharynx and contributes to immune defense. Its presence means that the region participates not only in particle trapping and transport but also in biological protection. In biology, this provides an example of respiratory anatomy containing specialized tissue associated with immune function.
Air moving through the nasopharynx encounters a mucosal lining that traps particles in mucus, while cilia direct the captured material toward the throat. These actions add protective processing to airflow. Consequently, the region can be studied as an active interface between inhaled air and respiratory defenses, rather than as a passive channel.
Key features include the mucosal lining, mucus, cilia, auditory tube openings, and lymphoid tissue such as the pharyngeal tonsil. Together, they represent airway protection, material transport, middle-ear ventilation, and immune defense. Organizing observations around these features allows researchers and students to connect regional anatomy with several physiological functions.
The nasopharynx is relevant to respiratory infection research because it lies along the route of inhaled air and contains mucus that can trap particles. Its mucosal surface and associated defenses provide a context for studying transmission or detection. Investigations can therefore connect infection-related questions with airway structure, particle handling, and local immune features.