Parenchymal Transection

Parenchymal transection is the controlled division of an organ’s functional tissue, typically during surgical resection, to remove diseased regions while preserving viable structures. The procedure separates parenchymal cells and connective tissue planes containing blood vessels, bile ducts, or other conduits; careful dissection and sealing or ligation of these structures limit bleeding and fluid leakage. In biology and biomedical research, studying parenchymal transection helps clarify tissue architecture, wound responses, and organ regeneration. Clinically, the technique is central to procedures such as hepatic resection, where precise tissue division can remove tumors or damaged tissue while protecting remaining organ function.

Parenchymal Transection - Related Videos

Research

JoVE Journal - Medicine

Techniques of Laparoscopic Right Posterior Sectionectomy: Glissonian Approach and a Parenchymal Transection Technique

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2023

Here, we present a protocol to perform laparoscopic right posterior sectionectomy, focusing on two key aspects: the intrahepatic Glissonian approach for inflow control and a parenchymal transection technique using an ultrasonic surgical aspirator.

Right Hemihepatectomy by Suprahilar Intrahepatic Transection of the Right Hemipedicle using a Vascular Stapler

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Cited by 1 •

2010

This video describes a right hemihepatectomy with intrahepatic transection of the right hemipedicle leaving the hepatoduodenal ligament completely untouched.

Isolation and Cannulation of Cerebral Parenchymal Arterioles

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Cited by 28 •

2016

This manuscript describes a simple and reproducible protocol for isolation of intracerebral arterioles (a group of blood vessels encompassing parenchymal arterioles, penetrating arterioles and pre-capillary arterioles) from mice, to be used in pressure myography, immunofluorescence, biochemistry, and molecular studies.

Research

JoVE Journal - Medicine
Free Sample

Laparoscopic Anatomical Liver Segment VII Resection with Liver Parenchymal Transection Following a Priority Approach

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2025

This protocol involves a laparoscopic anatomical resection of liver segment VII with liver parenchymal transection following a priority approach. This technique is unaffected by anatomical variations.

Preparing Cerebral Endothelial Tubes from Mouse Parenchymal Arterioles

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2025

This video demonstrates a method for isolating the endothelial tubes from mouse cerebral parenchyma. Through a combination of enzymatic digestion and mechanical dissociation, the process yields an intact tube with endothelial cells.

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