Pathology Review
Pathology Review - Related Videos
01:27
Systematic Reviews
0 Views •
2026
A systematic review is a rigorous, transparent method for identifying, evaluating, and combining all relevant research to address a specific question. For instance, a review might examine whether exercise reduces anxiety. Unlike narrative reviews, systematic reviews follow predefined protocols to reduce bias and ensure comprehensive coverage of the available evidence. Many follow the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, which include...
01:30
Peer Review Explained
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2026
Peer review is a central quality-control process in academic publishing. Before research is shared with the scholarly community, experts in the relevant field evaluate manuscripts to ensure that the findings are accurate, original, and methodologically sound. This review process helps maintain the reliability of the scientific record and reinforces trust in published literature. Submission and Editorial Screening The process begins when an author submits a manuscript to an academic journal. The...
01:24
Evaluating the Effect of a Synbiotic Formulation on Alzheimer’s Disease Pathology in Drosophila
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2025
Take a transgenic Drosophila.The brain of the Drosophila expresses the human amyloid peptide protein or APP and a cleaving enzyme.The enzyme cleaves APP, enabling the formation of beta-amyloid plaque, which leads toAlzheimer's disease or AD pathology in Drosophila.Feed the Drosophila AD model a diet containing a synbiotic formulation.The formulation contains a combination of three bioactive probiotic bacteria and a prebiotic.Inside the fly's gut, the prebiotic supports the growth and survival...
08:29
Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans
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Cited by 7 •
2016
Organized brain cutting procedures are necessary to correlate specific neuropsychiatric phenomena with definitive neuropathologic diagnoses. Brain cuttings are performed differently based on various clinico-academic contingencies. This protocol describes a symmetric bihemispheric brain cutting procedure to investigate hemispheric differences in human brain pathologies and to maximize current and future biomolecular/neuroimaging techniques.
01:13
Review and Preview
0 Views •
2023
Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
FAQs
Interpretation begins by comparing observed changes with normal anatomy and physiology. Alterations in cells, tissues, organs, or body fluids can then be related to processes such as inflammation, infection, neoplasia, or tissue degeneration. This biological comparison helps explain how illness develops and how structural abnormalities affect function.
Gross examination provides an overall view of visible structural changes, whereas microscopy reveals details at the cellular and tissue levels. Using both perspectives allows investigators to connect large-scale abnormalities with microscopic evidence. Their combined findings create a more complete basis for recognizing disease-related patterns and interpreting biological changes.
Biomarkers provide measurable features that can support disease identification or classification. When structural findings do not provide enough information, immunohistochemistry or molecular analysis may add relevant laboratory evidence. These tests extend the review beyond appearance alone, helping connect observed abnormalities with specific biological characteristics or disease mechanisms.
A review generally brings together clinical findings, examination of the specimen or body fluid, and evaluation of gross and microscopic features. If additional clarification is needed, laboratory tests such as immunohistochemistry or molecular analysis are considered. The findings are then integrated to support interpretation, classification, and assessment of disease effects.
These laboratory approaches become relevant when examination of structure alone does not fully resolve an abnormality or when additional biomarker information is needed. Immunohistochemistry and molecular analysis can supplement gross and microscopic observations, providing evidence for disease classification and mechanism. Their use therefore depends on the information required from the evaluation.
In biology, pathology review helps learners and researchers connect normal biological organization with disease progression. In applied settings, its findings can contribute to diagnosis, disease classification, and treatment planning. Research applications also include examining how illness changes over time and investigating the mechanisms underlying inflammation, infection, neoplasia, or degeneration.