Population Isolation

Population isolation is the separation of members of a species into groups that experience limited gene flow, a process that can shape genetic diversity and evolution. Isolation may result from geographic barriers such as mountains or rivers, differences in habitat or breeding time, or reproductive incompatibilities that prevent successful mating or offspring production. Once separated, populations accumulate distinct mutations and are influenced by natural selection, genetic drift, and local environmental conditions. Studying population isolation helps explain adaptation and speciation while guiding conservation strategies that preserve genetic variation and reconnect fragmented habitats.

Population Isolation - Related Videos

Research

JoVE EoE - Leukemia

Side Population Assay: A Method to Isolate Side Population of Tumor Cells from Zebrafish

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2023

The following protocol describes a method for isolating the side population of T-cell Acute Lymphoblastic Leukemia (T-ALL) tumor cells, consisting of stem cells, from an adult Zebrafish. The side population lacks prominent cell markers and hence we use Hoechst 33342 dye efflux assay to isolate them.

Isolation of the Side Population in Myc-induced T-cell Acute Lymphoblastic Leukemia in Zebrafish

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Cited by 5 •

2017

Here, we describe a technique to isolate the side population cells from a zebrafish model of myc-induced T-cell acute lymphoblastic leukemia (T-ALL). This side population assay is highly sensitive and is described for zebrafish T-ALL, but it may be applicable to other malignant and non-malignant zebrafish cell types.

Education

JoVE Lab Manual - Biology

Population Growth - Student Protocol

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2019

Exponential Population Growth Model ExpandNOTE: In these experiments you will use computer software to simulate different types of growth models. HYPOTHESES: The experimental hypothesis might be that if we increase either R, the reproductive rate or the initial population size, NT, that this will increase the population size after 10 generations in an exponential growth model compared to unmanipulated control populations. The null hypothesis may be that populations of different R and initial...

Population Growth - Concepts

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2019

Population Models An ecological population is a group of individuals of a single species living in an area at the same time. To persist, a population must either grow or maintain its size. Population ecology is the study of how population size and age distribution change over time through interactions with other species and the environment as well as with individuals of their own species. A particularly important feature that is studied by ecologists is the rate at which a population grows or...

Conservation of Small Populations

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2019

Small population sizes put a species at extreme risk of extinction due to a lack of variation, and a consequent decrease in adaptability. This weakens the chances of survival under pressures such as climate change, competition from other species, or new diseases. Large populations are more likely to survive pressures such as these, as such populations are more likely to harbor individuals that have genetic variants that are adaptive under new stresses. Small populations are much less likely to...

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