Renal Pelvis
Renal Pelvis - Related Videos
03:20
Intrarenal Injection of E. coli into the Renal Pelvis of a Rat
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2026
Source: Gupta, K., et al. Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis. J. Vis. Exp. (2017).This video demonstrates the intrarenal injection of E. coli into the renal pelvis of an anesthetized rat to induce a localized kidney infection, modeling acute pyelonephritis. It highlights key surgical steps and aseptic techniques necessary for establishing a reproducible in vivo infection model for downstream analysis.
03:36
Hydrodynamic Renal Pelvis Injection: A Technique to Directly Deliver DNA into Kidney Cells of Murine Model
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2023
In this video, we present the protocol for hydrodynamic injection of plasmids into the renal pelvis of the mouse kidney for nucleic acid transfection. This technique allows organ-specific delivery of plasmids by utilizing the principle of high hydrostatic pressure, which forcefully drives the plasmids into the specific site without causing tissue injury.
08:26
Hydrodynamic Renal Pelvis Injection for Non-viral Expression of Proteins in the Kidney
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Cited by 10 •
2018
This protocol describes a method to inject plasmid DNA into the mouse kidney via the renal pelvis to produce transgene expression specifically in the kidney.
06:38
Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats
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Cited by 14 •
2016
Early stage hemodynamic dysfunction is critical to the development of kidney disease. Yet, detection methodologies are limited. Recent advances in sonography provide a noninvasive, accurate option for early detection of kidney injury. This study outlines a step-by-step, sonographic methodology for detecting kidney dysfunction using a drug-induced nephrotoxicity rat model.
07:38
Isolating and Imaging Live, Intact Pacemaker Regions of Mouse Renal Pelvis by Vibratome Sectioning
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Cited by 1 •
2021
The goal of this protocol is to isolate intact pacemaker regions of the mouse renal pelvis using vibratome sectioning. These sections can then be used for in situ Ca2+ imaging to elucidate Ca2+ transient properties of pacemaker cells and other interstitial cells in vibratome slices.
FAQs
Urine follows an organized drainage sequence: it leaves the renal papillae, enters the minor calyces, and then passes into the major calyces. These larger collecting spaces merge before reaching the renal pelvis. This arrangement channels urine from kidney tissue into a single outflow region, allowing subsequent transport toward the ureter.
Smooth muscle contractions and pressure gradients work together to propel urine from the renal pelvis into the ureter. Contractions provide active movement, while pressure differences help establish a directional flow. Their coordinated action is important because urine must progress away from the kidney rather than remain within the collecting spaces.
Obstruction interferes with the normal passage of urine from the kidney toward the urinary tract. Because the renal pelvis is part of the drainage route, blockage there can reveal problems with kidney outflow and may be associated with hydronephrosis, kidney stones, or other urinary tract disorders. Its anatomy therefore has diagnostic importance.
The renal pelvis serves as the collecting and directing region formed by the merging major calyces, whereas the ureter continues the route toward the bladder. The pelvis links the kidney's urine-producing tissue with the ureter, and muscular activity and pressure gradients then support movement along this connected pathway.
Imaging the renal pelvis can help evaluate the kidney's drainage pathway and the connection between collecting structures and the ureter. Its appearance provides anatomical context when clinicians investigate hydronephrosis, kidney stones, or other urinary tract disorders. Studying this region can therefore support recognition of abnormal urine transport or obstruction.
The renal pelvis illustrates how urine-producing kidney tissue connects with the rest of the urinary tract. Examining its relationship with the papillae, calyces, ureter, and bladder clarifies how urine is collected and transported. This anatomical context also links basic biology with medical imaging and the study of drainage disorders.