Simple Epithelium

Simple epithelium is a single layer of epithelial cells that covers body surfaces, lines internal cavities, and supports controlled exchange between tissues and their environments. Its cells maintain apical-basal polarity and connect through junctions, allowing the tissue to combine selective permeability with barrier function; substances may cross by diffusion, active transport, or regulated secretion. Cell shape and specialization produce forms such as simple squamous, cuboidal, and columnar epithelium, each suited to different transport or lining roles. In biology, recognizing these arrangements helps interpret histological sections, relate structure to organ function, and understand how epithelial injury or abnormal growth can disrupt exchange, absorption, filtration, or protection.

Simple Epithelium - Related Videos

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JoVE Core - Anatomy and Physiology
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Classification of Epithelial Tissues: Simple Epithelium

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2025

Simple epithelium consists of a single layer of cells that lines body cavities and blood vessels. The shape of the cells in the epithelium reflects the function of the tissue. Cells in simple squamous epithelium appear as thin scales with flat, elliptical nuclei that mirror the form of the cell. Because of the thinness of the cells, simple squamous epithelium is present where the rapid passage of chemical compounds is observed. For example, the endothelium that lines the capillaries and vessels...

Research

JoVE EoE - Rodent Models

Isolation of Circumvallate Papillae (CVP) Epithelium from Mouse Model: An Enzymatic Procedure to Separate CVP Epithelium from Mouse Tongue

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2025

In this video, we describe the isolation of circumvallate papillae (CVP) epithelium from a murine tongue.

Multielectrode Array Recordings of the Vomeronasal Epithelium

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Cited by 14 •

2010

Multielectrode array (MEA) recordings provide a method for studying the electrical activity of large populations of neurons. Here, we present the details of a MEA preparation to record from the mouse vomeronasal epithelium while simultaneously stimulating the tissue.

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JoVE Lab Manual - Chemistry
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Simple Distillation - Concepts

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2020

Distillation of a Miscible Mixture Some liquids will evaporate entirely over time if left in an open container at room temperature. However, this evaporation process can be significantly accelerated if the liquid is heated. As the liquid is heated, the molecules within it gain the energy to escape the liquid phase and transition into the gas phase in the form of bubbles. This phenomenon is called boiling. Vapor Pressure Consider a closed container of liquid. Initially, some of this liquid...

Near Infrared (NIr) Light Increases Expression of a Marker of Mitochondrial Function in the Mouse Vestibular Sensory Epithelium

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Cited by 4 •

2015

Mitochondrial dysfunction is a hallmark of cellular senescence. This paper uses non-invasive near-infrared (NIr) treatment to improve mitochondrial function in the aging mouse vestibular sensory epithelium.

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