Sleep Disorders
Sleep Disorders - Related Videos
01:24
Substance Use Disorders Affecting Sleep
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2024
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue. Understanding the concepts of physical dependence,...
01:15
REM Sleep Behavior Disorder
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2024
REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner. RBD is significantly associated with...
09:23
High-Definition Transcranial Direct Current Stimulation During Sleep
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2025
This protocol describes high-definition transcranial direct current stimulation during sleep with simultaneous electroencephalography monitoring to investigate causal relationships between targeted brain regions and sleep as well as its related processes.
08:45
Polygraphic Recording Procedure for Measuring Sleep in Mice
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Cited by 55 •
2016
The recording of electroencephalogram (EEG) and electromyogram (EMG) in freely behaving mice is a critical step to correlate behavior and physiology with sleep and wakefulness. The experimental protocol described herein provides a cable-based system for acquiring EEG and EMG recordings in mice.
04:33
Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder
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2024
Here, we present a protocol that investigates the relationship between cognitive symptoms and sleep quality in patients with major depressive disorder. The THINC-integrated tool and polysomnography were used to evaluate cognitive symptoms and sleep quality.
FAQs
Circadian misalignment disrupts the timing of sleep relative to the body’s biological regulation of sleep and wakefulness. This mechanism differs from problems caused primarily by altered neural pathways or repeated interruptions from breathing and muscle activity. Studying the timing pattern helps biologists relate disrupted sleep to changes in brain activity, hormones, metabolism, and behavior.
Altered neural pathways can disturb the regulation of sleep and wakefulness, while breathing or muscle-related problems can interrupt sleep repeatedly after it begins. These mechanisms affect sleep in different ways: one changes control of the sleep-wake state, whereas the others fragment ongoing sleep. Distinguishing them helps researchers connect observed physiological patterns with possible disease mechanisms.
Sleep disorders provide a way to examine how brain activity interacts with hormones, metabolism, and behavior. Disrupted sleep may therefore be studied as part of a broader biological system rather than as an isolated nighttime event. Linking these domains helps researchers investigate disease mechanisms and evaluate whether restoring healthy sleep could improve whole-body function.
Evaluation can draw on sleep histories, physiological monitoring, and laboratory studies. Sleep histories describe patterns reported over time, while physiological monitoring supplies measurable information about sleep-related bodily activity. Laboratory studies add controlled biological investigation. Together, these approaches help identify patterns relevant to diagnosis and support research into how particular disruptions affect sleep regulation.
Sleep histories and physiological monitoring provide complementary evidence about disrupted sleep. Histories help characterize the timing and experience of sleep, while monitoring contributes measurable physiological patterns that may not be captured by description alone. Researchers can use these forms of evidence to support diagnostic work, investigate disease mechanisms, and compare biological findings across studies.
Researchers study Sleep Disorders when they need to connect disrupted sleep with biological mechanisms and measurable patterns that can guide treatment development. Findings from histories, physiological monitoring, and laboratory studies may clarify how sleep regulation is affected. This research also examines whether restoring healthy sleep could improve brain-related processes, metabolism, hormones, behavior, and broader whole-body function.