Soma
Soma - Related Videos
10:58
Fabrication of a Microfluidic Device for the Compartmentalization of Neuron Soma and Axons
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Cited by 14 •
2007
In this video we demonstrate the technique of soft lithography with polydimethyl siloxane (PDMS) which we use to farbricate a microfluidic device for culturing neurons.
03:06
Quantification of Retinal Ganglion Cell Somas Following Cauterization-Induced Ocular Hypertension
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2025
Source: Lani-Louzada, R., et al. Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents. J. Vis. Exp. (2022).This video demonstrates the quantification of retinal ganglion cells from chemically fixed rat retinas subjected to full-circle cauterization of the limbal vascular plexus. The process includes permeabilization, antibody staining, and nuclear counterstaining, followed by visualization under an epifluorescence microscope to assess the impact of...
06:15
Ultrafast Laser-Ablated Nanoparticles and Nanostructures for Surface-Enhanced Raman Scattering-Based Sensing Applications
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Cited by 1 •
2023
Ultrafast laser ablation in liquid is a precise and versatile technique for synthesizing nanomaterials (nanoparticles [NPs] and nanostructures [NSs]) in liquid/air environments. The laser-ablated nanomaterials can be functionalized with Raman-active molecules to enhance the Raman signal of analytes placed on or near the NSs/NPs.
08:34
Investigation into Deep Breathing through Measurement of Ventilatory Parameters and Observation of Breathing Patterns
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Cited by 3 •
2019
Here, we present a protocol to assess two deep breathing patterns of natural and diaphragmatic breathing for their effectiveness and ease of execution. Fifteen participants were selected, utilizing an electrocardiograph and expired gas analyzer for measurement of the ventilatory parameters, together with visual assessment by video capture of thoracoabdominal movement.
13:37
Extracellularly Identifying Motor Neurons for a Muscle Motor Pool in Aplysia californica
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Cited by 23 •
2013
In animals with large identified neurons (e.g. mollusks), analysis of motor pools is done using intracellular techniques1,2,3,4. Recently, we developed a technique to extracellularly stimulate and record individual neurons in Aplysia californica5. We now describe a protocol for using this technique to uniquely identify and characterize motor neurons within a motor pool.
FAQs
The nucleus and other organelles within the soma support neuronal maintenance by coordinating genetic activity, metabolism, and protein production. These functions provide the materials and energy needed for the neuron to remain viable and sustain communication. Examining intracellular activity in this region helps researchers connect cellular maintenance with broader changes in neuronal performance.
Signals arriving through dendrites are integrated in the soma before they influence electrical activity in the axon. This makes the cell body an important stage between incoming information and downstream neuronal signaling. Studying this integration helps researchers understand how a neuron combines multiple inputs rather than treating each dendritic signal as an isolated event.
Protein synthesis in the soma supplies proteins needed for ongoing cellular function and communication. Because neurons must maintain their internal operations while processing signals, disruption of this activity could affect both survival and signaling capacity. Investigating protein production in the cell body therefore links molecular activity with the neuron’s ability to function within neural circuits.
Changes in soma size or shape can serve as indicators of altered neuronal health. Researchers may use these structural differences to identify cellular changes associated with disrupted function or disease-related processes. Morphological analysis is therefore valuable because it connects visible features of the cell body with broader questions about neuronal condition.
The soma provides a cellular focus for examining how neurons maintain themselves while developing and establishing communication. Researchers can relate its structure and intracellular functions to changes in neuronal organization and activity over time. This perspective supports investigations of how individual neurons contribute to the formation and function of larger neural circuits.
The soma is examined because its structure and intracellular functions connect neuronal survival, signal processing, and communication. Alterations in this region may indicate changes relevant to brain function or neurodegenerative disease. Studying the cell body can therefore help researchers relate cellular abnormalities to disrupted neural circuits and broader changes in nervous-system performance.