Speckle Pattern

A speckle pattern is a granular distribution of bright and dark regions produced when coherent light, such as laser light, scatters from a rough or complex surface and the resulting waves interfere. In biological imaging, the pattern changes as scattering structures move, because motion alters the relative phase and intensity of the interfering light; analyzing these temporal fluctuations can provide information about tissue dynamics. Speckle-based methods are therefore used to monitor blood flow, microcirculation, cell movement, and other changes in living tissues. They offer noninvasive, wide-field measurements that support studies of physiology, disease progression, and responses to treatment.

Speckle Pattern - Related Videos

Research

JoVE Journal - Neuroscience

How to Build a Laser Speckle Contrast Imaging (LSCI) System to Monitor Blood Flow

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Cited by 25 •

2010

This video demonstrates how to build a Laser Speckle Contrast Imaging (LSCI) system that can easily be used to monitor blood flow.

Live Cell Imaging of F-actin Dynamics via Fluorescent Speckle Microscopy (FSM)

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Cited by 8 •

2009

Selection, microinjection, and imaging of fluorescently-labeled F-actin via fluorescent speckle microscopy (FSM).

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation

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Cited by 9 •

2016

Speckle tracking echocardiography is an emerging diagnostic imaging technique for the quantitative assessment of global and regional myocardial performance. Standard view echocardiographic motion images are recorded and deformation parameters are subsequently measured by automated continuous frame-by-frame tracking and motion analysis of speckles within the B-mode images of the myocardium.

Research

JoVE Journal - Bioengineering
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Applying Permanent, Robust Stenciled Patterns of Fine Particles to Elastomeric Surfaces

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2025

We present a method to apply permanent markings and patterns to silicone surfaces by adhering fine particles to the surface. The markings can be either a recognizable design or a random speckle pattern such as those used in digital image correlation.

Patterned Photostimulation with Digital Micromirror Devices to Investigate Dendritic Integration Across Branch Points

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Cited by 14 •

2011

Digital micromirror devices (DMD) can generate complex patterns in time and space with which to control neuronal excitability. Issues relevant to the design, construction, and operation of DMD systems are discussed. Such a system enabled the demonstration of non-linear integration across distal dendritic branch points.

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