Synovial Joints

Synovial joints are freely movable connections between bones that enable controlled movement while maintaining skeletal stability. In these joints, smooth articular cartilage covers the bone ends, a fibrous capsule encloses the joint cavity, and the synovial membrane produces lubricating fluid that reduces friction and helps distribute loads; ligaments further guide and limit motion. Common examples include the knee, shoulder, hip, and elbow, each shaped to support movements such as bending, rotation, or gliding. Studying synovial joints is central to biology because their structure explains normal locomotion and the effects of injuries, inflammation, cartilage degeneration, and disorders such as arthritis.

Synovial Joints - Related Videos

Education

JoVE Core - Anatomy and Physiology

Structural Joints: Synovial Joints

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2025

Synovial joints are the most common type of joint in the body. A key structural characteristic for a synovial joint is the presence of a joint cavity. This fluid-filled space is where the articulating surfaces of the bones contact each other. Also, unlike fibrous or cartilaginous joints, the articulating bone surfaces at a synovial joint are not directly connected to each other with fibrous connective tissue or cartilage. This gives the bones of a synovial joint the ability to move smoothly...

Development of the Limb Synovial Joints

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2023

Joints form during embryonic development in conjunction with the formation and growth of the associated bones. The embryonic tissue that gives rise to all bones, cartilage, and connective tissues of the body is called mesenchyme. The mesenchymal stem cells differentiate into chondrocytes that form the hyaline cartilage, and later the cartilaginous model of the bone. This model further transforms into a bone. This process is known as endochondral ossification. During development, the limbs...

Research

JoVE Journal - Medicine

Anterior Cruciate Ligament Transection and Synovial Fluid Lavage in a Rodent Model to Study Joint Inflammation and Posttraumatic Osteoarthritis

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2025

Herein, we describe a surgical method to transect the anterior cruciate ligament (ACL) as a reliable model to induce knee osteoarthritis in rodents and methodologies for harvesting knee synovial fluid, measuring knee edema, and assessing osteoarthritis severity.

Harvesting Articular Cartilage From Joints of an Equine Donor: A Surgical Procedure to Isolate Vascular Connective Tissue From Cadaveric Joints of an Equine Donor

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2025

In this video, we demonstrate the extraction of articular cartilage from an equine cadaveric joint. The isolated articular cartilage can be used for further downstream analysis.

Isolation and Cellular Phenotyping of Mesenchymal Stem Cells Derived from Synovial Fluid and Bone Marrow of Minipigs

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Cited by 5 •

2016

A protocol establishing mesenchymal stem cells (MSCs) isolated from the synovial fluid and bone marrow of minipigs and non-invasively collected using syringe aspiration is presented. Cellular phenotyping was performed using flow cytometry after cell isolation and in vitro cultivation of bone marrow and synovial fluids derived from MSCs.

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