Weaning Pups
Weaning Pups - Related Videos
15:00
Fundamentals of Breeding and Weaning
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2016
Source: Kay Stewart, RVT, RLATG, CMAR; Valerie A. Schroeder, RVT, RLATG. University of Notre Dame, IN Millions of mice and rats are bred for use in biomedical research each year. Worldwide, there are several large commercial breeding facilities that supply mice to research laboratories, but many facilities also choose to breed mice and rats in-house to reduce costs and increase research options. When breeding in the animal facility, researchers are able to manipulate the genetics of the...
02:34
Long-Term Continuous Electroencephalography Monitoring in a Rodent Pup
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2025
The video demonstrates long-term continuous electroencephalography (EEG) monitoring in rodent pups using a wireless transmitter system. The transmitter contains two recording electrodes and one reference electrode extending to the brain's surface. Upon placing the pup in a recording chamber, EEG can be continuously monitored throughout the pup's development into adulthood.
04:16
Inspiratory Muscle Training as an Adjunct to the Treatment of Weaning Failure in Critically Ill Patients: A Practical Guide
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2026
Respiratory muscle weakness is highly prevalent in patients weaning from mechanical ventilation. Resistive inspiratory muscle training (IMT) can improve inspiratory strength and potentially weaning outcomes. This protocol provides a structured approach to offer IMT to selected patients based on the best available knowledge, facilitating its wider application in critical care.
03:26
Transplantation of Interneuron Precursor Cells into the Brain of a Mouse Pup
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2025
Source: Quattrocolo, G., et al. Homochronic Transplantation of Interneuron Precursors into Early Postnatal Mouse Brains. J. Vis. Exp. (2018)This video demonstrates the transplantation of interneuron precursor cells into the neonatal mouse brain using either a homotopic or heterotopic approach. The procedure involves securing an anesthetized recipient pup, identifying the target brain region, and injecting a suspension of precursor cells derived from a donor pup at the same developmental stage.
09:35
Neurodevelopmental Reflex Testing in Neonatal Rat Pups
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Cited by 77 •
2017
Behavioral testing is the gold standard for determining outcomes following brain injury, and can identify the presence of developmental disabilities in infants and children. Neurodevelopmental reflexes are an early indicator of these abnormalities. A host of easily accomplished developmental reflex tests in the neonatal rodent were developed and described here.
FAQs
Developing teeth allow pups to handle foods beyond maternal milk, while increasing digestive capacity supports the use of solid foods. These changes make the transition progressive rather than immediate, because feeding abilities mature alongside nutritional needs. Observing both features helps explain how pups move toward greater independence while continuing to receive support during development.
The mother and littermates provide important social contact during this developmental stage. Pups can learn feeding behaviors through interactions with them, while the mother’s involvement reflects parental investment. These social influences connect nutrition with behavior, helping researchers examine how early feeding experiences contribute to independence and broader patterns of mammalian social development.
Timing affects how quickly pups experience changes in nutrition, feeding behavior, and independence. Because growth and health depend on nutritional requirements being met during development, poorly matched timing or management may influence stress, growth, health, and survival. Studying these relationships helps clarify how developmental transitions shape later outcomes in young mammals.
Management should support a gradual reduction in milk intake while pups gain experience with solid food. Increasingly varied foods can be introduced as feeding abilities develop, while continued contact with the mother and littermates supports learning. This approach reflects the biological sequence of changing nutrition, developing independence, and acquiring feeding behavior rather than treating weaning as a single event.
Research on weaning pups can reveal how nutrition, growth, parental investment, social behavior, and independence develop together. The transition provides a focused way to examine changing nutritional requirements and feeding behavior in young mammals. Findings can also help explain how early developmental conditions relate to health, stress, and survival across different settings.
Knowledge about this transition is relevant in laboratory, domestic, and conservation settings, where management can affect pup health, growth, stress, and survival. The same developmental principles may be examined under different conditions, allowing researchers and caretakers to consider both nutritional needs and social influences when supporting young mammals through increasing independence.