Conscious Sedation

Conscious sedation is a medically supervised state in which medications reduce anxiety, discomfort, and awareness during a procedure while allowing a patient to respond purposefully to verbal or light physical stimulation. It works through carefully titrated sedative and analgesic drugs that depress central nervous system activity without routinely producing complete unconsciousness, with continuous monitoring of breathing, circulation, oxygenation, and responsiveness. In cancer research, conscious sedation can support biopsies, endoscopic examinations, image-guided interventions, and other procedures needed to obtain tumor samples or assess treatment effects. Its appropriate use may improve procedural tolerance, data collection, and participant experience while preserving safety through structured monitoring.

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Research

JoVE Journal - Behavior

Conscious and Non-conscious Representations of Emotional Faces in Asperger's Syndrome

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Cited by 5 •

2016

An EEG experimental protocol is designed to clarify the interplay between conscious and non-conscious representations of emotional faces in patients with Asperger's syndrome. The technique suggests that patients with Asperger's syndrome have deficits in non-conscious representation of emotional faces, but have comparable performance in conscious representation with healthy controls.

Education

JoVE Core - Pharmacology

Sedatives and Hypnotics: Overview

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2024

Sedatives are drugs that alleviate anxiety, while hypnotics induce sleep. Both classes of medication suppress neuronal activity, leading to a calming effect for sedatives and facilitating sleep for hypnotics. Sedative-hypnotics are categorized into barbiturates, benzodiazepines (BZDs), and non-benzodiazepines or Z-drugs. These drugs work by suppressing central nervous system activity, and this suppression is dose-dependent. Older sedative medications, like barbiturates, follow a linear curve in...

Understanding Consciousness

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2024

Consciousness can be defined as the state of being aware of and able to think about one's existence, sensations, and surroundings. It encompasses two major components: awareness and arousal. Awareness pertains to the recognition of environmental stimuli and internal states. At the same time, arousal refers to the physiological readiness to engage with these stimuli, which varies significantly between states like sleep and wakefulness. Sleep, a crucial state, is characterized by reduced physical...

Conscious Marketing

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2024

Conscious marketing refers to a business approach that values and promotes integrity, transparency, and customer welfare. It's a shift away from traditional transactional marketing towards a value-based exchange that seeks to build relationships and foster trust between companies and their customers. The significance of conscious marketing lies in its potential to create long-term success for businesses. By focusing on the needs and interests of the consumers, companies can build strong...

Research

JoVE Journal - Behavior
Free Sample

SECONDs Administration Guidelines: A Fast Tool to Assess Consciousness in Brain-injured Patients

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Cited by 29 •

2021

These guidelines can be used for the administration of the Simplified Evaluation of CONsciousness Disorders (SECONDs), a short behavioral tool developed to diagnose brain-injured patients in time-constrained settings. This scale examines command-following, communication, visual pursuit, fixation, pain localization, oriented movements and arousal.

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