Mammary Tumor Resection
Mammary Tumor Resection - Related Videos
03:58
Brain Tumor Resection in a Mouse Using a Minimally Invasive Resection System
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2025
Source: Alomari, S., et al. Implementation of Minimally Invasive Brain Tumor Resection in Rodents for High Viability Tissue Collection. J. Vis. Exp. (2022)This video demonstrates the use of a minimally invasive resection system (MIRS) to excise tumor tissue from an anesthetized mouse implanted with a tumor. The procedure involves securing the mouse onto a stereotactic frame, reopening the previous surgical site to access the brain, and inserting a specialized cannula that utilizes suction and a...
07:55
The Influence of Liver Resection on Intrahepatic Tumor Growth
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Cited by 6 •
2016
A high incidence of tumor recurrence after resection of liver metastases remains an unsolved problem. The illustrated mouse model may be useful to investigate the reasons for such recurrences. It combines a liver resection model with intrahepatic tumor cell injection for the first time.
04:40
Augmented Reality-Based Visualization of a Resected Tumor Specimen
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2026
Source:Carly Fassler1, Liyu Huang1, Kavita Prasad1, Jiayi Xu2, Guansen Tong2, Jie Ying Wu2, Michael C. Topf1,31Department of Otolaryngology – Head and Neck Surgery, Vanderbilt University Medical Center.2Computer Science Department, Vanderbilt University.3Vanderbilt University School of Engineering, Vanderbilt University.This video demonstrates using augmented reality (AR) for tumor resection, where a 3D-scanned tumor specimen is visualized as a hologram on a head-mounted display. Surgeons can...
05:06
Fluorescence-guided Tumor Resection and MSC-seeded Scaffold Implantation in Murine Model: A Surgical Procedure to Deliver Therapeutic Mesenchymal Stem Cells into Brain Tumor Resection Cavity in Mouse Model
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2025
This video presents the surgical procedure for image-guided tumor resection and implantation of a bio-scaffold seeded with genetically engineered mesenchymal stem cells or MSCs expressing tumor necrosis factor-related apoptosis-inducing ligand or TRAIL. These therapeutic MSCs have the potential in treatment of brain tumors.
07:59
Translationally-Relevant Tumor Resection Model for Murine Preclinical Models of Oral Squamous Cell Carcinoma
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2026
A unique method to surgically resect oral squamous cell carcinoma tumors established in the oral cavity is shown here.
FAQs
Careful separation of the tumor from surrounding tissue helps retain viable mammary tissue whenever possible. This supports more consistent evaluation of the local tissue environment and allows investigators to compare tumor material with adjacent tissue. Preserving non-tumor tissue also helps standardize analyses of local responses, wound healing, and biological changes after surgery.
Standardized handling of tumor exposure, tissue separation, bleeding control, and wound closure reduces procedural variation between animals or experimental groups. Greater consistency improves reproducibility and makes treatment outcomes easier to interpret. It also helps distinguish effects associated with an adjuvant therapy or tumor biology from differences introduced by the surgical technique itself.
Follow-up studies can examine whether disease recurs, how the surgical wound heals, and how tumors respond to adjuvant therapies. These outcomes connect the local surgical event with broader cancer biology. Comparing recurrence or healing patterns with tissue-based findings can help investigators relate structural, molecular, and immunological observations to treatment response.
Collected tumor and adjacent tissue provide complementary material for histological, molecular, and immunological analyses. Tumor samples can characterize the lesion, while nearby tissue offers context for changes surrounding the tumor site. Using both sources supports a more complete interpretation of tumor biology and may clarify how local tissue conditions relate to recurrence or therapy response.
The procedure prioritizes clear exposure of the mammary gland, controlled separation of the tumor from surrounding tissue, effective control of bleeding, and closure of the surgical site. These priorities protect remaining viable tissue and promote consistent recovery. Applying them uniformly is important when surgical outcomes will be compared across experimental groups.
This approach is useful when investigators need both a localized intervention and tissue for direct analysis. It supports studies of tumor biology, recurrence, wound healing, and responses to adjuvant treatment. Because the procedure also emphasizes animal welfare and reproducibility, it can provide a consistent experimental framework for evaluating disease progression and therapeutic outcomes.