Mesenteric Excision
Mesenteric Excision - Related Videos
07:51
Mesenteric Artery Contraction and Relaxation Studies Using Automated Wire Myography
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Cited by 37 •
2011
An automated myography method for force measurements in isolated mesenteric arteries is described. It employs a Mulvany-Halpern Auto Dual Wire Myograph 510A to determine responses to phenylephrine and extracellular calcium. The method allows consistent determination of isometric responses to agonists in small vessels of diameters of 60 - 300 μm, independently.
01:54
Base Excision Repair
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2020
One of the common DNA damages is the chemical alteration of single bases by alkylation, oxidation, or deamination. The altered bases cause mispairing and strand breakage during replication. This type of damage causes minimal change to the DNA double helix structure and can be repaired by the base excision repair (BER) pathways. BER corrects damaged DNA sequences by removing the damaged base and restoring the original base sequence using the complementary strand as a template. The first step of...
10:32
In Vitro Recording of Mesenteric Afferent Nerve Activity in Mouse Jejunal and Colonic Segments
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Cited by 8 •
2016
Mesenteric afferent nerves convey information from the gastrointestinal tract towards the brain regarding normal homeostasis as well as pathophysiology. Gastrointestinal afferent nerve activity can be assessed by mounting isolated intestinal segments with attached afferent nerves into an organ bath, isolating the nerve, and assessing basal as well as stimulated activity.
04:55
Mesenteric Lymph Duct Cannulation in a Rat Model to Harvest Lymph Fluid
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2025
This video demonstrates a technique to cannulate the mesenteric lymph duct in rats. This method enables direct access to the entire volume of components present in the lymph fluid.
03:08
Single-port Robotic Transanal Total Mesorectal Excision in a Porcine Model (Sus scrofa domesticus)
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2026
This protocol demonstrates Single-port (SP) robotic transanal total mesorectal excision (taTME) in a porcine model, highlighting procedural feasibility, technical steps, and preclinical applicability for minimally invasive rectal surgery.
FAQs
Following these planes helps organize the dissection around the mesentery’s natural structural boundaries. Preserving the specimen’s envelope can maintain the relationship among bowel, vessels, lymphatic channels, nerves, and lymph nodes. That continuity gives researchers and pathologists a more reliable basis for evaluating margins, nodal distribution, and the completeness of the resected tissue.
The mesentery contains lymphatic channels and lymph nodes that can provide a route and record of tumor dissemination. Examining the resected tissue in relation to these structures allows cancer researchers to study patterns of lymph-node involvement and possible spread through lymphatic pathways. These observations can contribute to research on staging and recurrence patterns.
Controlling vessels supplying the involved bowel segment supports removal of the associated mesenteric tissue as a connected specimen. At the same time, preserving its structural envelope helps retain the anatomical relationships needed for assessment. This combination is relevant to evaluating specimen quality and to studying how vascular and lymphatic anatomy relates to oncologic findings.
The procedure generally includes dissecting along selected anatomical or embryological planes, removing the mesentery together with the involved bowel segment, and controlling the vessels supplying that segment. Maintaining the specimen’s structural envelope is also important. Together, these steps create tissue that can be assessed for margins, lymph-node involvement, and quality in a standardized manner.
Researchers can evaluate surgical margins, the presence and distribution of involved lymph nodes, and overall specimen quality. These measurements help connect the extent and technical quality of resection with staging accuracy and treatment planning. When collected consistently, they also provide data for comparing surgical approaches and investigating patterns associated with recurrence.
By retaining the bowel segment and its associated mesenteric tissue, the specimen can show how tumor findings relate to lymphatic pathways and regional lymph nodes. Margin assessment and nodal evaluation then supply information relevant to staging and treatment decisions. Across studies, these standardized observations can help researchers examine links between surgical technique, specimen quality, and recurrence patterns.