Surgical Implantation Procedure

A surgical implantation procedure is a controlled operation that places biological material, tissue, or an experimental device within a defined anatomical site, enabling researchers to study disease or test interventions under reproducible conditions. The process typically involves anesthesia, aseptic preparation, a carefully planned incision, precise placement, and wound closure, followed by monitoring for recovery and complications. In cancer research, implantation can establish tumor models by introducing tumor cells or tissue into laboratory animals, allowing investigators to examine tumor growth, invasion, treatment response, and therapeutic delivery. Standardized technique improves model consistency and supports more reliable evaluation of anticancer strategies.

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JoVE EoE - Rodent Models

Surgical Implantation of Temperature Telemetric Monitoring System in Mouse Model: A Surgical Procedure to Implant Temperature Telemetric Device to Measure Mouse Core Body Temperature

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2025

In this video, we describe a surgical procedure to implant a temperature telemetric device in a mouse model to continuously measure its core body temperature.

Implantation of Cranial Imaging Window in Mouse Model: A Surgical Procedure to Implant Glass-based Coverslip for Stable Optical Access to Regions of Murine Brain

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2023

This video presents a surgical procedure to implant cranial window in a mouse model for stable optical access to different regions of the brain.

Research

JoVE Journal - Biology
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Surgical Technique for the Implantation of a Biomimetic Artificial Intervertebral Disc in a Goat Animal Model

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2025

This study presents a novel surgical technique for implanting a biomimetic artificial intervertebral disc (BioAID). The method ensures precise placement and stability, aiming to restore cervical spine function using a goat model. This technique shows promise for clinical application in both human and canine patients suffering from cervical spine myelopathy.

Continuous Drug Infusion System in Mouse Model: A Surgical Procedure to Implant Micro-osmotic Pump Infusion System in the Mouse Brain for Continuous Drug Delivery

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2025

In this video, we demonstrate the assembly of a micro-osmotic pump brain infusion system followed by its surgical implantation in the mouse skull. This system enables continuous delivery of potential drugs and facilitates the study of their effects on the brain and brain tissue.

Surgical Implant Procedure and Wiring Configuration for Continuous Long-Term EEG/ECG Monitoring in Rabbits

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Cited by 2 •

2025

The study outlines a protocol for the design, manufacturing, and placement of a novel continuous EEG/ECG recording system in rabbits. This hard-wired system allows for continuous EEG/ECG recordings from nine distinct electrodes on the head and chest, which facilitates comprehensive assessments of electrical activity in the brain and heart.

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