Aggregation Growth Analysis

Aggregation growth analysis is the study of how molecules, particles, or clusters associate and increase in size over time, providing insight into reaction behavior, material formation, and stability. It examines processes such as nucleation, particle collision, coalescence, and surface-controlled growth by tracking changes in particle size, concentration, morphology, or scattering response under defined chemical conditions. In chemistry, these measurements help characterize crystallization, precipitation, colloidal assembly, and unwanted aggregation in solutions, allowing researchers to compare growth kinetics, identify controlling variables such as concentration and temperature, and design materials or formulations with targeted properties.

Aggregation Growth Analysis - Related Videos

Research

JoVE EoE - Neuropathology

In Vitro Assessment of Aggregated Amyloid-β on Neuronal Growth Cone Collapse

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2025

This video demonstrates an in vitro assessment of neuronal growth cone collapse by amyloid-β (Aβ) aggregates. Treating the neurons with Aβ aggregates causes cytoskeletal destabilization, leading to the collapse of growth cones at the tip of the axons. The treated cells are compared with control cells to assess the extent of growth cone collapse.

Precise, High-throughput Analysis of Bacterial Growth

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Cited by 56 •

2017

Quantitative evaluation of bacterial growth is essential to understanding microbial physiology as a systems-level phenomenon. A protocol for experimental manipulation and an analytical approach are introduced, allowing for precise, high-throughput analysis of bacterial growth, which is a key subject of interest in systems biology.

Education

JoVE Science Education - Environmental Sciences

Bacterial Growth Curve Analysis and its Environmental Applications

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2023

Source: Laboratories of Dr. Ian Pepper and Dr. Charles Gerba - The University of Arizona Demonstrating Author: Luisa Ikner Bacteria are among the most abundant life forms on Earth. They are found in every ecosystem and are vital for everyday life. For example, bacteria affect what people eat, drink, and breathe, and there are actually more bacterial cells within a person’s body than mammalian cells. Because of the importance of bacteria, it is preferable to study particular species of bacteria...

A Turbidimetric Analysis to Monitor Collagen-Induced Aggregation of Pretreated Human Platelets

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2025

This video demonstrates turbidimetric analysis to assess collagen-induced platelet aggregation in pre-treated, washed human platelets. Control wells show collagen-induced aggregation, whereas a high concentration of inhibitors blocks Pannexin-1 channels, thereby inhibiting collagen-induced platelet aggregation, evident from unchanged turbidity.

Lentiviral-Mediated Transduction of Human Neurons for Tau Protein Aggregation Analysis

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2025

This video demonstrates the process of transducing human neuronal cells with a lentivirus encoding a mutant human tau protein tagged with yellow fluorescent protein (YFP) to study protein aggregation. It outlines the steps from viral entry to mutant tau expression, culminating in the formation of visible cytoplasmic tau aggregates in the neurons.

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