Degasser System
Degasser System - Related Videos
08:18
Degassing Liquids with Freeze-Pump-Thaw Cycling
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2023
Source: Laboratory of Dr. Neil Branda — Simon Fraser University Degassing refers to the process by which dissolved gases are removed from a liquid. The presence of dissolved gases such as oxygen or carbon dioxide can impede chemical reactions that utilize sensitive reagents, interfere with spectroscopic measurements, or can induce unwanted bubble formation. A number of different techniques are available for degassing liquids; some of these include heating, ultrasonic agitation, chemical...
02:56
Ultrasound-Induced Neuromodulation Using a Microelectrode Array System
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2025
This video demonstrates the method for inducing the modulation of neural activity in cultured human iPSC-derived neurons in a multi-well microelectrode array, or MEA system using a focused ultrasound transducer.
10:58
SNARE-mediated Fusion of Single Proteoliposomes with Tethered Supported Bilayers in a Microfluidic Flow Cell Monitored by Polarized TIRF Microscopy
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Cited by 8 •
2016
Here, we present a protocol to detect single, SNARE-mediated fusion events between liposomes and supported bilayers in microfluidic channels using polarized TIRFM, with single molecule sensitivity and ~15 msec time resolution. Lipid and soluble cargo release can be detected simultaneously. Liposome size, lipid diffusivity, and fusion pore properties are measured.
07:01
Improved Polydimethylsiloxane (PDMS) Double Casting via Silicone Oil Treatment for Densely Packed Microstructure Replication
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2025
This protocol presents an improved demolding procedure for the Polydimethylsiloxane (PDMS) double casting technique by introducing silicone oil as a non-adhesive barrier between PDMS layers. Unlike plasma or chemical surface modification methods, this approach requires no specialized or costly equipment, making it a more accessible and cost-effective alternative.
08:15
Modeling Healthy and Dysbiotic Vaginal Microenvironments in a Human Vagina-on-a-Chip
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Cited by 6 •
2024
This article describes a protocol for creating a microfluidic vagina-on-a-chip (Vagina Chip) culture device that enables the study of human host interactions with a living vaginal microbiome under microaerophilic conditions. This chip can be used as a tool to investigate vaginal diseases as well as to develop and test potential therapeutic countermeasures.
FAQs
When the liquid pressure decreases, dissolved gases such as oxygen, nitrogen, and carbon dioxide can diffuse out of the solvent. Vacuum-based operation strengthens this pressure-driven removal, while a gas-permeable membrane provides a surface through which the gases can leave. Removing these gases reduces the chance that they will interfere with later measurements or fluid handling.
These approaches provide different ways to promote gas removal from liquids. Vacuum and pressure reduction lower the conditions that keep gases dissolved, whereas a gas-permeable membrane allows diffusion through a specialized barrier. The overview also identifies sparging and ultrasonic energy as alternative approaches, so degasser designs can use more than one physical strategy.
Dissolved gases can create bubbles, disturb liquid flow, and contribute to baseline fluctuations during analysis. Oxygen can also promote oxidation, which may alter chemical conditions. These effects reduce measurement reliability even when the solvent itself appears suitable, making gas removal important when stable flow, controlled chemistry, and reproducible analytical signals are required.
The solvent is directed through a degassing system before it enters the analytical process. Depending on the device, the system lowers pressure, applies vacuum, uses a gas-permeable membrane, or applies another supported degassing approach. The treated solvent can then be used in techniques such as high-performance liquid chromatography or electrochemistry.
Solvent degassing is useful in high-performance liquid chromatography when dissolved gases could form bubbles, destabilize flow, or produce baseline fluctuations. Removing those gases before analysis supports more reliable operation and improves measurement consistency. The process therefore helps the chromatographic system deliver more reproducible results while reducing gas-related interference with the instrument.
In electrochemistry, removing dissolved gases helps limit effects that can disturb measurements, including oxygen-related oxidation and gas-associated instability. More broadly, effective degassing improves measurement accuracy, protects instrumentation, and supports reproducible experimental results. These benefits make solvent treatment relevant when the experiment depends on stable chemical conditions and dependable analytical responses.