Abnormal Movement Observation

Abnormal movement observation is the systematic assessment of involuntary, excessive, reduced, or poorly coordinated movements to identify clinically meaningful changes in motor function. Clinicians examine movement at rest and during posture, action, and targeted tasks, noting features such as rhythm, speed, amplitude, distribution, triggers, and effects of distraction or sensory input. These observations help distinguish tremor, chorea, dystonia, tics, myoclonus, and other movement patterns associated with neurological dysfunction. In clinical practice, structured observation supports differential diagnosis, guides selection of additional examinations or tests, and provides a baseline for monitoring disease progression and treatment response.

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Research

JoVE Journal - Neuroscience

Observation of the Ciliary Movement of Choroid Plexus Epithelial Cells Ex Vivo

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Cited by 6 •

2015

In this study, a detailed light microscopic technique was optimized for real-time observation and analysis of the motion of CPEC cilia ex vivo together with an electron microscopic method for ultrastructural analysis.

Cell Death Associated with Abnormal Mitosis Observed by Confocal Imaging in Live Cancer Cells

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Cited by 13 •

2013

The cytotoxic activity of the phenanthridine PJ-34 in cancer cells undergoing mitosis was documented in real time by live confocal imaging. PJ-34 eradicated human breast cancer MDA-MB-231 cells harboring extra-centrosomes in mitosis. Unlike normal bi-focal mitosis, the extra-centrosomes were not clustered in the two spindle poles in the presence of PJ-34.

Education

JoVE Science Education - Clinical Skills

Observation and Inspection

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2023

Source: Jaideep S. Talwalkar, MD, Internal Medicine and Pediatrics, Yale School of Medicine, New Haven, CT Observation and inspection is fundamental to physical examination and begins at the first point of contact with a patient. While observation and inspection are often used interchangeably, observation is a general term that refers to the careful use of one's senses to gain information. Inspection is an act limited to what one can observe visually, and when referring to physical examination,...

Abnormal Proliferation

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2021

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...

Observational Research

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2023

Source: Laboratories of Gary Lewandowski, Dave Strohmetz, and Natalie Ciarocco—Monmouth University If you want to know how someone thinks or feels, you can ask that person questions. Another approach is to observe how the person is acting or look for indicators of how they acted in the past. While observations may seem revealing, it isn’t always easy to know if they are truly accurate. For instance, you may see a person smiling and assume they are happy, when in reality they are annoyed and...

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