Bladder Neck Obstruction

Bladder neck obstruction is a blockage or narrowing at the bladder outlet that restricts urine flow from the bladder into the urethra, making it an important cause of lower urinary tract symptoms. It develops when structural changes, such as scar tissue or prostate-related compression, or abnormal bladder-neck muscle activity increases outlet resistance, which can lead to straining, weak stream, incomplete emptying, and urinary retention. Clinical evaluation typically combines symptom assessment, physical examination, urine testing, and measurements of urinary flow or residual volume to identify the underlying cause. Accurate diagnosis guides treatment and helps prevent complications such as recurrent infections, bladder dysfunction, and kidney impairment.

Bladder Neck Obstruction - Related Videos

Research

JoVE Journal - Medicine

Nerve-sparing Mid-urethral Obstruction (NeMO) in Female Small Rodents

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Cited by 7 •

2017

Traditional modeling of partial bladder outlet obstruction in rodents is fraught with animal mortality. A denervation injury from dissection around the proximal urethra and bladder neck is also of major concern. We developed and evaluated a safe and reliable mid-urethral obstruction model, avoiding the shortcomings of the traditional model.

Unilateral Ureteral Obstruction Murine Model: A Surgical Procedure to Obstruct the Urinary Flow from a Kidney in Mouse Models

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2023

This video demonstrates the procedure to generate a unilateral ureteral obstruction mouse model. The procedure involves cutting one of the ureters of the mouse to obstruct urine flow.

Holmium:YAG Laser-Assisted Induction of Bladder Neck Contracture in a Rat Model

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2026

This protocol demonstrates transvesical Ho:YAG laser ablation to create a reproducible rat model of bladder neck fibrosis for studying thermal injury-induced fibrotic remodeling and therapeutic interventions.

A Murine Model of Irreversible and Reversible Unilateral Ureteric Obstruction

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Cited by 47 •

2014

The murine model of irreversible unilateral ureteric obstruction (UUO) is presented together with the model of reversible UUO in which the ureteric obstruction is relieved by anastomosis of the severed ureter into the bladder. These models enable the study of renal inflammation and scarring as well as tissue remodeling.

Education

JoVE Science Education - Clinical Skills

Neck Exam

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2023

Source: Robert E. Sallis, MD. Kaiser Permanente, Fontana, California, USA Examination of the neck can be a challenge because of the many bones, joints, and ligaments that make up the underlying cervical spine. The cervical spine is composed of seven vertebrae stacked in gentle C-shaped curve. The anterior part of each vertebra is made up of the thick bony body, which is linked to the body above and below by intervertebral discs. These discs help provide stability and shock absorption to the...

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