Clinical Diagnosis
Clinical Diagnosis - Related Videos
01:25
Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis
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2026
Type 2 diabetes mellitus develops gradually and is often asymptomatic in early stages.Clinical ManifestationsWhen symptoms appear, they include fatigue, blurred vision, pruritus, delayed wound healing, and recurrent infections, particularly candidal infections. Peripheral neuropathy may present as numbness or tingling in the extremities. Classic hyperglycemia symptoms—polyuria, polydipsia, and polyphagia—are less common. Most patients are overweight and frequently have associated hypertension...
07:34
FISH for Pre-implantation Genetic Diagnosis
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Cited by 17 •
2011
This article describes the selection of suitable probes for single-cell FISH, spreading techniques for blastomere nuclei, and in situ hybridization and signal scoring, applied to pre-implantation genetic diagnosis (PGD) in a clinical setting.
08:43
Diagnosis of Musculus Gastrocnemius Tightness - Key Factors for the Clinical Examination
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Cited by 12 •
2016
Isolated Musculus gastrocnemius tightness is a common cause for foot and ankle pathologies. Currently no standardized examination procedure exists. This manuscript demonstrates that 20 degree of knee flexion eliminates the restraining effect of the M. gastrocnemius on ankle dorsiflexion and presents a video description of a standardized examination protocol.
07:50
Establishment of a Clinic-based Biorepository
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Cited by 4 •
2017
Cutaneous tumors are often discarded following Mohs micrographic surgery. A protocol is described here that enables clinical support staff to effectively process and store cutaneous tumor (e.g., squamous cell carcinoma, basal cell carcinoma, and melanoma) samples for downstream laboratory applications without interfering with clinical operations.
01:22
Nursing Diagnosis
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2023
Following assessment, a nursing diagnosis is the next step in the nursing process. It begins after the nurse has collected and recorded the patient data. The purpose of diagnosing is to identify how the client responds to actual or potential health processes, identify factors that bestow or that cause health problems, the etiologies, and identify resources or strengths the individual, group, or community can draw on to prevent or resolve problems. The nursing diagnosis focuses on evidence-based...
FAQs
A differential diagnosis organizes several plausible explanations for a patient’s findings rather than committing prematurely to one possibility. Clinicians compare each candidate condition with the signs, symptoms, history, examination results, laboratory data, and imaging findings available. This comparison helps identify which explanation best accounts for the overall pattern and supports more appropriate treatment and risk assessment.
Different sources of clinical evidence contribute distinct information about a patient’s condition. History and symptoms describe the patient’s experience, physical examination adds directly observed findings, and laboratory tests or imaging provide additional investigative results. Integrating these sources allows clinicians to evaluate how consistently a possible diagnosis explains the complete clinical picture instead of relying on one observation.
Standardized diagnostic criteria provide a shared framework for deciding whether observed findings support a particular condition. By reducing variation in how clinicians describe and classify cases, they improve communication and make comparisons across patients more meaningful. In clinical research, consistent criteria also help investigators evaluate diagnostic methods and interpret findings across studies or patient groups.
The workflow begins with gathering the patient’s signs, symptoms, and medical history, followed by a physical examination. Clinicians then select and interpret relevant laboratory tests, imaging, or other investigations. Results are integrated into a differential diagnosis, after which the most supported explanation guides care. Subsequent assessments can evaluate treatment response or reveal disease progression.
Laboratory tests, imaging, and other investigations add evidence that may clarify or refine the possibilities identified from the patient’s history and examination. Their results are interpreted together with clinical findings rather than viewed in isolation. This integrated approach helps clinicians compare competing diagnoses, select treatment more appropriately, and establish information for ongoing monitoring.
A well-supported diagnosis helps clinicians select a suitable treatment, assess risks, and estimate prognosis, meaning the expected course of the condition. Repeated diagnostic assessment can show whether care is working or whether disease progression has occurred. In research, standardized diagnostic approaches allow new diagnostic methods to be evaluated using comparable patient groups and outcomes.