Congenital Heart Defects

Congenital heart defects are structural abnormalities of the heart or major blood vessels that develop before birth and can disrupt circulation, making them an important focus of clinical care. They arise when cardiac structures, such as the chambers, septa, valves, or great vessels, do not form normally, potentially causing abnormal shunting, restricted blood flow, or reduced oxygen delivery. Clinicians assess these conditions through physical examination, prenatal imaging, echocardiography, and other diagnostic tests. Management may include observation, medication, catheter-based procedures, or surgery, depending on the defect and its effects. Early detection and lifelong follow-up can improve outcomes and guide personalized care.

Congenital Heart Defects - Related Videos

Research

JoVE Journal - Medicine
Free Sample

Implantation of Total Artificial Heart in Congenital Heart Disease

0 Views •

Cited by 40 •

2014

This is a case report of a patient with congenitally corrected transposition of the great arteries (CCTGA) who received a total artificial heart (TAH) as a bridge to heart transplant. The TAH was successfully implanted with modifications to accommodate the patient's congenitally malformed heart.

Research

JoVE Journal - Developmental Biology

Analysis of Congenital Heart Defects in Mouse Embryos Using Qualitative and Quantitative Histological Methods

0 Views •

Cited by 4 •

2020

In this protocol, we describe procedures to qualitatively and quantitatively analyze developmental phenotypes in mice associated with congenital heart defects.

A Pipeline to Characterize Structural Heart Defects in the Fetal Mouse

0 Views •

Cited by 1 •

2022

This article details murine congenital heart disease (CHD) diagnostic methods using fetal echocardiography, necropsy, and Episcopic fluorescence image capture (EFIC) using Episcopic confocal microscopy (ECM) followed by three-dimensional (3D) reconstruction.

Education

JoVE Science Education - Clinical Skills

Cardiac Exam III: Abnormal Heart Sounds

0 Views •

2023

Source: Suneel Dhand, MD, Attending Physician, Internal Medicine, Beth Israel Deaconess Medical Center Having a fundamental understanding of normal heart sounds is the first step toward distinguishing the normal from the abnormal. Murmurs are sounds that represent turbulent and abnormal blood flow across a heart valve. They are caused either by stenosis (valve area too narrow) or regurgitation (backflow of blood across the valve) and are commonly heard as a "swishing" sound during auscultation.

Analysis of Coronary Vessels in Cleared Embryonic Hearts

0 Views •

Cited by 11 •

2016

We present a protocol for the analysis of coronary vessels in whole embryonic murine hearts up to E15.5, using standard immunological staining methods followed by optical clearance and confocal microscopy. This technique enables visualization of blood vessels throughout the entire heart without the need for time-consuming analysis of serial sections.

View All Results

FAQs

Related Topics