Hypotension

Hypotension is abnormally low blood pressure that may reduce blood flow to organs and become clinically important when it causes inadequate tissue perfusion. It can result from decreased blood volume, reduced cardiac output, excessive vasodilation, or impaired autonomic regulation, with severity influenced by how rapidly blood pressure falls and the individual’s underlying condition. In clinical practice, assessment combines blood pressure measurement with symptoms, physical findings, medical history, and evaluation for causes such as dehydration, bleeding, infection, medication effects, or cardiac dysfunction. Recognizing the underlying mechanism guides fluid therapy, medication adjustment, treatment of the cause, and monitoring for organ injury.

Hypotension - Related Videos

Research

JoVE Journal - Medicine

2-Vessel Occlusion/Hypotension: A Rat Model of Global Brain Ischemia

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Cited by 35 •

2013

Bilateral carotid occlusion coupled with systemic hypotension produces global brain ischemia in the rat, resulting in damage to the hippocampus with reproducible severity. Animal subjects are impaired with predictable patterns of brain damage, they recover expediently, and mortality rates are comparatively low.

Echocardiographic Assessment Using Subxiphoid-Only Examination for Hypotensive Patients

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2025

The protocol here provides a rapid, phenotype-based approach for focused ultrasound evaluation of the hypotensive patient, using subcostal images of the inferior vena cava and heart, with additional views of the upper lungs and pleural spaces.

Ultrasound Cyclo Plasty in Eyes with Glaucoma

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Cited by 17 •

2018

Glaucoma is a chronic disease with progressive degeneration of optic nerve fibers resulting in decreased visual field. Elevated intraocular pressure is considered the most important and the only treatable risk factor. This manuscript describes a simple, surgeon-friendly, non-incisional technique, named Ultrasound Cyclo Plasty, for reducing intraocular pressure in glaucoma patients.

A Swine Model of Neonatal Asphyxia

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Cited by 50 •

2011

Large animal models have good translational values in the examination of physiology and pharmacology of neonatal asphyxia. Using newborn piglets, we develop an experimental protocol to simulate neonatal asphyxia which has advantages of studying the systemic and regional hemodynamics, oxygen transport with biochemical and pathologic pathways and correlations.

Research

JoVE Journal - Medicine
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Quantitative Autonomic Testing

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Cited by 179 •

2011

Standardized, comprehensive and fully quantitative testing of autonomic functions is described. The autonomic tests consist of evaluation of all three major autonomic domains including cardiovagal, adrenergic and sudomotor. The severity and distribution of dysautonomia is quantitated using Composite Autonomic Severity Scores.

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