Barrel Vaults
Barrel Vaults - Related Videos
03:28
Functional Magnetic Resonance Spectroscopy of the Rat Barrel Cortex During Whisker Stimulation
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2025
Source: Blanc, J., et al. Functional Magnetic Resonance Spectroscopy at 7 T in the Rat Barrel Cortex During Whisker Activation. J. Vis. Exp. (2019)This video demonstrates the method of analyzing metabolic changes in the rat barrel cortex using functional magnetic resonance spectroscopy during whisker stimulation. Baseline metabolite spectra are compared with stimulated spectra to detect lactate increase in the barrel cortex, confirming successful neuronal activation.
11:08
Double-barreled and Concentric Microelectrodes for Measurement of Extracellular Ion Signals in Brain Tissue
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Cited by 19 •
2015
We demonstrate the fabrication, calibration and properties of two types of ion-selective microelectrodes (double-barreled and concentric) for measurement of ion concentrations in brain tissue. These are then used in the mouse hippocampal slice preparation to show that excitatory activity changes both extracellular potassium and sodium concentrations.
09:55
From Constructs to Crystals – Towards Structure Determination of β-barrel Outer Membrane Proteins
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Cited by 8 •
2016
β-barrel outer membrane proteins (OMPs) serve many functions within the outer membranes of Gram-negative bacteria, mitochondria, and chloroplasts. Here, we hope to alleviate a known bottleneck in structural studies by presenting protocols for the production of β-barrel OMPs in sufficient quantities for structure determination by X-ray crystallography or NMR spectroscopy.
01:09
Multi-pass Transmembrane Proteins and β-barrels
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2023
In multi-pass transmembrane proteins, the polypeptide chain crosses the membrane more than once. The transmembrane polypeptide chain either forms an α-helix or β-strand structure. α-Helix containing multi-pass transmembrane proteins are ubiquitous, whereas β-strand containing ones are mainly found in gram-negative bacteria, mitochondria, and chloroplasts. α-Helix containing multi-pass transmembrane proteins Multi-pass transmembrane proteins such as G-protein-linked receptors (GPCRs) and...
09:26
Functional Magnetic Resonance Spectroscopy at 7 T in the Rat Barrel Cortex During Whisker Activation
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Cited by 4 •
2019
After checking by blood-oxygen-level-dependent functional magnetic resonance imaging (BOLD fMRI) that the corresponding somatosensory barrel field cortex area (called S1BF) is correctly activated, the main goal of this study is to quantify lactate content fluctuations in the activated rat brains by localized proton magnetic resonance spectroscopy (1H-MRS) at 7 T.
FAQs
Gravity loads follow the curved structural path of the vault, producing compression along the arch rather than relying only on bending across a flat span. These compressive forces continue toward the supporting walls, piers, or abutments. The curvature distributes loading along the vault’s length, while the supports must receive the resulting forces safely.
The curved load path generates forces that act not only downward but also laterally at the supports. If walls, piers, or abutments cannot resist this lateral thrust, the vault may not maintain its intended structural behavior. Evaluating thrust is therefore essential when selecting support conditions and determining whether the proposed configuration can carry gravity loads safely.
Span, curvature, material strength, support conditions, and resistance to lateral thrust all affect performance. Span changes the distance over which loads must be carried, while curvature influences how forces are distributed. Material strength limits the capacity of the vault, and the support arrangement determines how compression and lateral forces are received.
Structural analysis examines the relationship among the vault’s span, curvature, materials, supports, and expected gravity-load behavior. Engineers use these factors to assess compression along the arch and the lateral thrust delivered to supporting elements. This evaluation helps determine whether the configuration is structurally appropriate and supports safe, efficient design decisions.
Barrel vaults may be built from masonry, concrete, steel, or other structural materials. Material selection matters because the vault’s performance depends partly on material strength and its ability to carry compression through the curved form. The chosen material must also work with the support conditions and the intended span of the covered space.
Their continuous form allows barrel vaults to cover elongated spaces such as corridors, tunnels, halls, and transportation infrastructure. In these applications, engineers must relate the vault’s geometry and material to the span and support arrangement. Structural analysis then helps evaluate load transfer and lateral thrust for the specific covered space.