Contrastive Learning

Contrastive learning is a machine-learning approach that learns useful representations by comparing related and unrelated examples, reducing reliance on manually labeled data. During training, the model encodes samples into a feature space, pulls positive pairs closer, and pushes negative pairs apart through a contrastive loss; positive pairs may come from augmented views of the same input, while negatives represent different inputs. In engineering, this method supports robust perception and pattern recognition for images, signals, language, and sensor data, including inspection and autonomous systems. Its ability to learn transferable features can improve performance when labeled datasets are limited or changing conditions make annotation costly.

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Research

JoVE Journal - Biology
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Phase Contrast and Differential Interference Contrast (DIC) Microscopy

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Cited by 26 •

2008

This protocol highlights the principles and practical applications of Phase and Differential Interference Contrast (DIC)...

Education

JoVE Core - Cell Biology

Phase Contrast and Differential Interference Contrast Microscopy

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2023

Phase-Contrast Microscopes In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...

Contrast Enhanced Vessel Imaging using MicroCT

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Cited by 17 •

2011

Contrast enhanced small animal vessel imaging by microCT is a rapid, cost-effective and high-throughput technique for serial in situ examination for tumor development, for analyzing the network of blood vessels that nourish them, and for following the response of tumors to preclinical therapeutic intervention(s).

An Introduction to Learning and Memory

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2023

Learning is the process of acquiring new information and memory is the retention or storage of that information. Different types of learning, such as non-associative and associative learning, and different types of memory, such as long-term and short-term memory, have been associated with human behaviors. Studying these components in detail helps behavioral scientists understand the neural mechanisms behind these two complex phenomena. JoVE's overview on learning and memory introduces common...

Contrast Imaging in Mouse Embryos Using High-frequency Ultrasound

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Cited by 4 •

2015

Here, we present a protocol to inject ultrasound microbubble contrast agents into living, isolated late-gestation stage murine embryos. This method enables the study of perfusion parameters and of vascular molecular markers within the embryo using contrast-enhanced high-frequency ultrasound imaging.

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