Electrospinning Nanofibers
Electrospinning Nanofibers - Related Videos
06:55
Fabrication of Small Caliber Stent-grafts Using Electrospinning and Balloon Expandable Bare Metal Stents
0 Views •
Cited by 10 •
2016
In the protocol, we present a method to manufacture a small caliber stent-graft by sandwiching a balloon expandable stent between two electrospun nanofibrous polyurethane layers.
07:58
Electrospinning of Silk Biomaterials
0 Views •
2023
Silk fibers have been processed and used to create fabrics and threads for centuries. However, the solubilizing of silk fibers, thereby turning it into a versatile pre-polymer solution is a much newer technology. Solubilized silk can be processed in many different ways to create a biocompatible material with controllable mechanical properties. This video introduces the processing of silk from silk worm cocoons, and shows how the silk solution can be used to create a fiber mat via...
14:43
Synthesis of Keratin-based Nanofiber for Biomedical Engineering
0 Views •
Cited by 12 •
2016
Electrospun nanofibers have a high surface area to weight ratio, excellent mechanical integrity, and support cell growth and proliferation. These nanofibers have a wide range of biomedical applications. Here we fabricate keratin/ PCL nanofibers, using the electrospinning technique, and characterize the fibers for possible applications in tissue engineering.
09:39
Procedure for Fabricating Biofunctional Nanofibers
0 Views •
Cited by 1 •
2012
An efficient approach for preparing nanofibers decorated with functional groups capable of specifically interacting with proteins is described. The approach first requires the preparation of a polymer functionalized with the appropriate functional group. The functional polymer is fabricated into nanofibers by electrospinning. The effectiveness of the binding of the nanofibers with a protein is studied by confocal microscopy.
09:32
Electrospun Nanofiber Scaffolds with Gradations in Fiber Organization
0 Views •
Cited by 5 •
2015
Here, we present a protocol to fabricate electrospun nanofiber scaffolds with gradated organization of fibers and explore their applications in regulating cell morphology/orientation. Gradients with regard to physical and chemical properties of the nanofiber scaffolds offer a wide variety of applications in the biomedical field.
FAQs
The applied electric field first deforms the fluid into a Taylor cone and then draws material into a slender charged jet. Electrostatic forces stretch the jet continuously, while solvent evaporation removes the liquid phase and leaves solid fibers. This sequence determines whether the collected material forms a continuous nanoscale fiber network rather than isolated droplets.
Material selection and processing conditions jointly influence fiber diameter, alignment, porosity, and composition. The polymer determines the available fiber-forming material, while the electrical and collection conditions affect how the charged fluid stretches and solidifies. Engineers adjust these variables to obtain structures suited to a particular mechanical, transport, sensing, or surface-area requirement.
Stretching reduces the jet to a very small diameter, whereas solvent evaporation converts the stretched fluid into a solid fiber before collection. If either stage does not produce the required transformation, the resulting structure may not achieve the intended continuity or nanoscale dimensions. Together, these processes create lightweight materials with tunable porous architectures.
Engineers can tailor fiber diameter, alignment, porosity, and composition through material choice and processing conditions. These features provide different design options without changing the basic fiber-forming approach. For example, a project may prioritize a porous structure for filtration, aligned fibers for a scaffold, or a particular composition for sensors and energy-storage devices.
A typical workflow selects a polymer solution or melt, places the feed in an arrangement that supports electric-field drawing, applies high voltage, and directs the resulting jet toward a collector. The jet stretches as it travels, solvent evaporates when a solution is used, and the solid fibers accumulate as a nanoscale mat or related structure.
The essential elements are a polymer solution or melt, a source of high voltage, a path for the charged fluid, and a collector where the fibers accumulate. Changing the polymer affects composition, while changing processing conditions influences the resulting architecture. These choices allow the same general setup to support different engineering material designs.
Their tunable diameter, porosity, alignment, composition, and high surface area support several engineering applications. Examples include filtration media, tissue scaffolds, sensors, protective coatings, and energy-storage materials. The lightweight fiber structures can be designed for advanced devices that benefit from nanoscale dimensions, large available surface area, or controlled material architecture.