A subscription to JoVE is required to view this content. Sign in or start your free trial.
Chapters
- 00:05Title
- 01:47Synthesis of α,ω-dihydroxyl Polymer [HO-PEO-P2MS-PEO-OH]
- 03:06The Functional Polymer: CDNP-PEO-P2MS-PEO-CDNP
- 03:44CDNP-PEO-P2MS-PEO-CDNP/SWCNT Solution
- 04:20Electrospinning of Polymer-CNT Composite
- 05:18Binding Specificity of Nanofibers with Anti-DNP IgE Protein
- 06:12Current-Voltage Behavior of Nanofibers
- 07:13Results: Functional Polymers of 2,4-dinitrophenyl
- 08:55Conclusion
An efficient approach for preparing nanofibers decorated with functional groups capable of specifically interacting with proteins is described. The approach first requires the preparation of a polymer functionalized with the appropriate functional group. The functional polymer is fabricated into nanofibers by electrospinning. The effectiveness of the binding of the nanofibers with a protein is studied by confocal microscopy.
Tags
FabricatingBiofunctional NanofibersElectrospinningFunctional GroupsMaterial-biomarker InteractionsBiosensorsSingle Molecule DetectorsEffective ApproachFunctional Polymers24-dinitrophenyl (DNP)Anti-DNP IgEPolymerizationDifunctional InitiatorElectron Transfer Reactionα-methylstyrenePotassium Metal2-methoxystyrene MonomerEthylene OxideLiving PolymerTermination By Methanolαω-dihydroxyl PolymerN-24-DNP-∈-amino Caproic AcidDCC Coupling
