Stereotactic Coordinates
Stereotactic Coordinates - Related Videos
10:35
Stereotactic Radiosurgery for Gynecologic Cancer
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Cited by 14 •
2012
Stereotactic body radiotherapy (SBRT) involves image-guided, ablative radiation delivered to cancer targets refractory to chemotherapy or to conventional radiation treatment. The robotic-armed Cyberknife SBRT system, using sophisticated target localization, delivers hypofractionated radiation doses capable of sterilizing cancer targets. This article will consider new therapeutic roles of SBRT for gynecological cancers.
02:57
Coordination Number and Geometry
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2020
For transition metal complexes, the coordination number determines the geometry around the central metal ion. Table 1 compares coordination numbers to molecular geometry. The most common structures of the complexes in coordination compounds are octahedral, tetrahedral, and square planar. Coordination Number Molecular Geometry Example 2 linear [Ag(NH3)2]+ 3 trigonal planar [Cu(CN)3]2− 4 tetrahedral(d0 or d10), low oxidation...
07:54
Applying Stereotactic Injection Technique to Study Genetic Effects on Animal Behaviors
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Cited by 15 •
2015
Stereotactic injection of lentiviruses expressing cDNAs or shRNAs can modulate gene expression in specific brain areas of mice. Here, we present a protocol to combine stereotactic injections with behavioral tasks, such as the Open Field Test (OFT) and the Forced Swim Test (FST).
02:54
Coordination Compounds and Nomenclature
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2020
In most main group element compounds, the valence electrons of the isolated atoms combine to form chemical bonds that satisfy the octet rule. For instance, the four valence electrons of carbon overlap with electrons from four hydrogen atoms to form CH4. The one valence electron leaves sodium and adds to the seven valence electrons of chlorine to form the ionic formula unit NaCl (Figure 1a). Transition metals do not normally bond in this fashion. They primarily form coordinate covalent bonds, a...
05:08
A Stereotactically Guided Ablation Technique for Auditory Cortex Removal in Rats
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2025
This video demonstrates a stereotactically-guided surgical procedure for ablating the auditory cortex in a rat. The steps include identifying anatomical landmarks in an anesthetized rat secured in a stereotactic frame, creating a window on the skull above the auditory cortex, aspirating the cortical layers, and providing post-operative care to assess the impact of the ablation on sound processing.
FAQs
The three axes divide a target location into independent directional measurements relative to defined anatomical landmarks. Together, they describe where an intervention or sample should be positioned in three dimensions rather than relying on a general region name. This coordinate structure helps researchers compare procedures across experiments and relate localized treatments to specific central nervous system responses.
Anatomical landmarks provide the reference points from which positional measurements are established. Using the same landmarks allows researchers to describe target locations consistently, even when different experiments involve separate animals or procedures. This shared reference system is especially important when comparing localized delivery, immune responses, or tissue samples across studies of neuroinflammation and infection.
Both approaches use spatial information to guide an instrument toward a selected anatomical target, but they provide that guidance through different systems. A stereotaxic frame supplies a structured physical reference for positioning, whereas imaging-based navigation uses anatomical imaging to support targeting. The choice affects how researchers establish and follow the planned three-dimensional trajectory.
They convert a target into standardized positional information instead of leaving its location to a broad anatomical description. Repeated use of the same coordinate references helps investigators deliver an intervention or collect a sample from a comparable site in different experiments. As a result, observed differences in neuroinflammation, host responses, or disease progression can be interpreted with greater confidence.
A researcher first identifies the anatomical target and expresses its position relative to established landmarks along the relevant axes. The coordinate information then guides an instrument through a stereotaxic frame or imaging-based navigation system. This approach links the planned position to a controlled intervention or sampling site, supporting consistent work in selected central nervous system tissues.
In immunology and infection studies, coordinate-guided procedures can support controlled delivery of pathogens, immune cells, antibodies, or drugs into selected tissues. The same positional framework can guide consistent sampling from the central nervous system. These capabilities allow investigators to examine localized effects rather than treating the entire system as a single undifferentiated site.
They are useful when researchers need to connect a precisely localized intervention with a subsequent biological response. Targeted delivery or sampling can help examine how pathogens, immune cells, antibodies, or drugs relate to neuroinflammation, host responses, and disease progression. Consistent positioning also strengthens comparisons between experimental groups and across repeated studies.