Anterior Circulation Stroke
Anterior Circulation Stroke - Related Videos
11:58
Minimally Invasive Thumb-sized Pterional Craniotomy for Surgical Clip Ligation of Unruptured Anterior Circulation Aneurysms
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Cited by 2 •
2015
Minimally invasive thumb-sized pterional craniotomy for aneurysm clipping has afforded our patients with a shorter hospital stay at a lower cost compared to the national average.
09:41
Performing and Processing FNA of Anterior Fat Pad for Amyloid
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Cited by 28 •
2010
Fat pad aspiration is a preferred, minimally invasive, and low cost approach as compared to other methods to detect amyloid for diagnosis of systemic amyloidosis. This video article demonstrates a procedural outline for performing fat pad aspiration with appropriate processing of the specimen for the optimal diagnostic outcome.
06:49
The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rNAION)
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Cited by 6 •
2016
The following report describes how to replicate the rodent model of nonarteritic anterior ischemic optic neuropathy (rNAION), using the appropriate dye, contact lens and laser parameters. We also reveal the appropriate steps for evaluating the rNAION lesion in vivo.
08:14
Modeling Stroke in Mice: Permanent Coagulation of the Distal Middle Cerebral Artery
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Cited by 103 •
2014
Various murine models of middle cerebral artery occlusion (MCAO) are widely used in experimental brain research. Here, we demonstrate the model of transcranial permanent distal MCAO which produces consistent cortical infarction of a size corresponding to damage imposed by the majority of human ischemic strokes.
03:24
Anterior Eye Segment Dissection: A Method to Isolate Cornea Bearing Anterior Segment from Porcine Eye
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2025
In this video, we demonstrate the dissection of the cornea-bearing anterior segment of the porcine eye. The isolated segment can be used for organ culturing to study the pathophysiology of eye disorders.
FAQs
The affected artery and brain region determine which functions are disrupted. Injury within territories supplied by the internal carotid, middle cerebral, or anterior cerebral arteries may produce different combinations of unilateral weakness or numbness, language impairment, visual field loss, and neglect. This territorial relationship helps clinicians connect neurological findings with the likely location of vascular injury.
Ischemic injury results from a thrombus or embolus blocking blood flow, which deprives neural tissue of oxygen and can produce an infarct. Hemorrhagic injury follows vessel rupture, allowing blood to accumulate and causing pressure-related damage. Because the underlying mechanisms differ, brain imaging is important for guiding the subsequent management approach.
Neural tissue can be damaged when an obstructed vessel interrupts oxygen delivery, so early recognition of neurological changes is important. Rapid neurological assessment identifies deficits such as weakness, language impairment, visual field loss, or neglect, while brain imaging helps characterize the injury. Together, these steps support timely treatment decisions and may improve outcomes.
Symptoms vary because injury does not affect the same brain region in every event. The involved vascular territory, whether supplied by the internal carotid, middle cerebral, or anterior cerebral artery, influences the functions placed at risk. Consequently, one person may show language impairment, while another may primarily experience sensory, motor, visual, or attentional changes.
Evaluation begins with a rapid neurological assessment to identify the pattern and severity of functional loss. Brain imaging then helps determine whether the event reflects ischemic injury or vessel rupture and supports localization of the affected area. These findings guide decisions about thrombolysis, mechanical thrombectomy, blood pressure management, and other immediate care.
For ischemic events, thrombolysis and mechanical thrombectomy are treatment options identified in the clinical pathway for restoring management of obstructed blood flow. Brain imaging and rapid neurological assessment help guide their use, while blood pressure management addresses an important aspect of acute care. The objective is to limit injury and support better neurological outcomes.
Acute treatment addresses the immediate vascular injury, but care also extends beyond the initial event. Secondary prevention is included to reduce the risk of further cerebrovascular problems, while rehabilitation supports recovery from impairments such as weakness, language difficulty, visual field loss, or neglect. These approaches also provide a foundation for studying mechanisms of recovery and rehabilitation.