Aortic Root Reconstruction

Aortic root reconstruction is a surgical procedure that repairs or replaces the section of the aorta attached to the heart, often while addressing associated aortic valve disease. Surgeons reshape or replace dilated or damaged tissue with a vascular graft and may preserve the native valve by reimplanting it within the graft, or replace the valve when preservation is not feasible. The procedure restores continuity between the left ventricle, aortic valve, and ascending aorta, helping prevent rupture, dissection, and progressive valve dysfunction. It is used in conditions such as aortic root aneurysm, dissection, connective-tissue disorders, and complex valve-root disease.

Aortic Root Reconstruction - Related Videos

Research

JoVE Journal - Medicine

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

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Cited by 4 •

2017

Full-root aortic valve replacement by stentless aortic xenograft is a viable option in patients with small aortic roots. We describe, a technique for the full-root implantation of stentless aortic xenografts, with emphasis on the management of the proximal suture line and coronary anastomoses, and discuss its limitations and alternative options.

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

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2017

Valve-sparing aortic root replacement has the advantage of preserving the patient's own aortic valve. The complexity of the reported techniques to date restricts their use to a limited number of cardiac surgeons. This protocol describes step-by-step a standardized technique reproducible by a greater number of cardiac surgeons.

Aortic Ring Assay

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Cited by 42 •

2009

Angiogenesis, the sprouting of blood vessels from pre-existing vasculature, is associated with both natural and pathological processes. Here we demonstrate an aortic ring assay that allows angiogenic potentiators and inhibitors to be directly added to aortic rings in culture. Sprouting and neovessel outgrowth can be determined by inspecting the aortic rings over a period of 6-12 days.

Isolation and Analysis of Aortic Arch and Root Lesions in an Atherosclerotic Mouse Model

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2025

This protocol provides a comprehensive methodology for the quantitative analysis of atherosclerotic plaques to facilitate more in-depth research into the mechanisms and progression of atherosclerosis.

Creation of Murine Experimental Abdominal Aortic Aneurysms with Elastase

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Cited by 55 •

2009

This video shows how to induce abdominal aortic aneurysms (AAA) in mice via transient intraluminal infusion of porcine pancreatic elastase into the infrarenal segment of the abdominal aorta. The model has the ability to add broad insight into the pathobiology of AAA due to the emergence of numerous transgenic and gene knockout mice.

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