Burst Pacing

Burst pacing is a medical technique that delivers a rapid, programmed train of electrical stimuli to control or assess excitable tissue, particularly the heart during arrhythmia management. In cardiac applications, pacing impulses delivered faster than the intrinsic rhythm can depolarize myocardial cells in succession, interrupt reentrant electrical circuits, or temporarily overdrive the heart, depending on the pacing protocol and tissue response. Electrophysiologists use burst pacing during programmed stimulation to induce or terminate tachyarrhythmias and evaluate cardiac conduction. The approach supports diagnosis, treatment planning, and assessment of therapies such as catheter ablation or implantable cardiac devices, while requiring careful control of timing and stimulation intensity.

Burst Pacing - Related Videos

Research

JoVE Journal - Medicine

Transesophageal Atrial Burst Pacing for Atrial Fibrillation Induction in Rats

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Cited by 6 •

2022

The present work describes an experimental protocol of transesophageal atrial burst pacing for efficient induction of atrial fibrillation (AF) in rats. The protocol can be used in rats with healthy or remodeled hearts, allowing the study of AF pathophysiology, identification of novel therapeutic targets, and evaluation of new therapeutic strategies.

Research

JoVE Journal - Medicine
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Translational Rabbit Model of Chronic Cardiac Pacing

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2023

We present a minimally invasive leporine model of long-term cardiac pacing that can be utilized for artificial pacing and heart failure development in preclinical studies.

An Assay to Assess Phagocytosis and Oxidative Burst Activity In Granulocytes and Monocytes

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2025

This video demonstrates the assay to confirm phagocytic activity by cells in human blood via flow cytometry. The granulocytes and monocytes confirm their phagocytic activity by showing green and red fluorescence confirming the presence of engulfed bacteria and oxidative burst activity respectively.

Quantification of the Respiratory Burst Response as an Indicator of Innate Immune Health in Zebrafish

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Cited by 16 •

2013

The innate immune response protects organisms against pathogen infection. A critical component of the innate immune response, the phagocyte respiratory burst, generates reactive oxygen species that kill invading microorganisms. We describe a respiratory burst assay that quantifies reactive oxygen species produced when the innate immune response is chemically induced.

Measuring Granulocyte and Monocyte Phagocytosis and Oxidative Burst Activity in Human Blood

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Cited by 5 •

2016

The purpose of this manuscript is to present a method for measuring monocyte and granulocyte phagocytosis and oxidative burst activity in human blood samples.

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