Chronic Obstructive Pulmonary Disease

Chronic obstructive pulmonary disease (COPD) is a common, preventable, and treatable lung disease characterized by persistent respiratory symptoms and airflow limitation, making it a major cause of disability and mortality. It develops when chronic inflammation narrows the airways, increases mucus production, and damages alveolar walls, reducing expiratory airflow and gas exchange. In medicine, clinicians use symptom assessment and spirometry to support diagnosis, while smoking cessation, inhaled bronchodilators, pulmonary rehabilitation, vaccination, and selected oxygen therapy can reduce symptoms, exacerbations, and functional decline. Studying COPD clarifies how environmental exposures, airway inflammation, and structural lung changes interact, supporting earlier intervention and more individualized care.

Chronic Obstructive Pulmonary Disease - Related Videos

Research

JoVE Journal - Medicine

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure

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Cited by 7 •

2017

This study describes the successful generation of a new chronic obstructive pulmonary disease (COPD) animal model by repeatedly exposing mice to high concentrations of ozone.

Education

JoVE Core - Anatomy and Physiology

Chronic Obstructive Pulmonary Disease

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2026

COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction. Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...

Acupoint Application as a Traditional Chinese Medicine Treatment for Fatigue Associated with Chronic Obstructive Pulmonary Disease

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2025

This protocol describes the specific process and efficacy of acupoint application in treating fatigue symptoms associated with chronic obstructive pulmonary disease.

Chronic Obstructive Pulmonary Disease-I: Introduction

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2024

Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.

Chronic Obstructive Pulmonary Disease-V: Management

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2024

Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies: Smoking Cessation Primary Step: The most critical intervention for all COPD patients who smoke. Benefits: Slows disease...

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