Clinical Frailty Screening

Clinical frailty screening is a structured assessment used to identify reduced physiological reserve and vulnerability to adverse outcomes during illness, treatment, or hospitalization. It combines information about function, mobility, cognition, comorbidity, and dependence in daily activities, often assigning a standardized frailty category from relatively fit to severely frail. In medicine, screening supports early recognition of patients who may need comprehensive geriatric assessment, individualized treatment planning, rehabilitation, or additional support. It can also inform discussions about prognosis and care goals, while complementing rather than replacing clinical judgment and diagnostic evaluation.

Clinical Frailty Screening - Related Videos

Research

JoVE Journal - Biology

Frailty Assessment in an Aging Mouse Model

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2025

The goal of the present protocol is to provide instructions and guidelines for assessing physical frailty in C57Bl/6x129J laboratory mice. Specific details regarding each measure used in the physical frailty index are explained. Several methods for reporting frailty results are also presented.

Research

JoVE Journal - Medicine
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Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty

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Cited by 22 •

2013

Frailty syndrome is commonly seen in the aged and reflects multi-system physiological change. However, with reduced functional reserve and resilience frailty is also known to be common in the HIV infected population. This study outlined an easily administered screening test to identify HIV patients with frailty. When significant components of frailty are identified, clinicians will be able to focus on amelioration of the problem and promote reversion to the pre-frail state.

Research

JoVE Journal - Medicine
Free Sample

Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty

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Cited by 18 •

2016

Persons infected with HIV are often frail, depressed and live a sedentary lifestyle for which conventional exercise is too taxing. Here, we present an exercise protocol that ameliorates aspects of frailty in HIV-infected persons. An exergame integrating cognitive control was developed using biosensors that measured balance, weight-shifting and obstacle crossing.

Using a Pan-Viral Microarray Assay (Virochip) to Screen Clinical Samples for Viral Pathogens

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Cited by 84 •

2011

The Virochip is a pan-viral microarray designed to simultaneously detect all known viruses as well as novel viruses on the basis of conserved sequence homology. Here we demonstrate how to run a Virochip assay to analyze clinical samples for the presence of both known and unknown viruses.

Identifying Frailty Using Point-of-Care Ultrasonography: Image Acquisition and Assessment

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2024

Here, we present a protocol to assess frailty in the perioperative setting using point-of-care ultrasound to measure quadriceps thickness. This method offers a practical, non-invasive alternative to traditional assessment methods, potentially enhancing perioperative care by quickly identifying frail patients.

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