Distal Tibial Allograft

Distal tibial allograft is a donor-derived segment of bone and cartilage harvested from the lower tibia and transplanted to restore damaged or deficient articular anatomy. In reconstructive surgery, the graft is shaped to match the recipient site, positioned against the bone defect, and secured with fixation screws so its structural support and cartilage surface can help re-establish joint stability and congruence. It is used most notably to reconstruct substantial glenoid bone loss in patients with recurrent shoulder instability, particularly when native bone is insufficient for standard repair. This technique can preserve joint anatomy and provide a biologic foundation for incorporation during healing.

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Research

JoVE EoE - Neuropathology

Generating a Rat Model of Tibial Neuroma Transposition

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2025

Source: Brakkee, E. M., et al. Surgery and Behavioral Testing in the Tibial Neuroma Transposition Model in Rats. J. Vis. Exp. (2023).This video demonstrates a procedure to generate a rat tibial neuroma transposition (TNT) model. After exposing the tibial nerve in the hind leg of an anesthetized rat, transect the nerve. Next, create a subcutaneous tunnel, thread the severed nerve through the tunnel, and suture it in place. In the absence of a target for reinnervation, disorganized axonal...

Tibial Nerve Transection - A Standardized Model for Denervation-induced Skeletal Muscle Atrophy in Mice

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Cited by 38 •

2013

The tibial nerve transection model is a well-tolerated, validated, and reproducible model of skeletal muscle atrophy. The model surgical protocol is described and demonstrated in C57Black6 mice.

Surgical Angiogenesis in Porcine Tibial Allotransplantation: A New Large Animal Bone Vascularized Composite Allotransplantation Model

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Cited by 5 •

2017

Currently any kind of vascularized composite allotransplantation depends on long-term-immunosuppression, difficult to support for non-life-critical indications. We present a new porcine tibial VCA model that can be used to study bone VCA and demonstrate the use of surgical angiogenesis to maintain bone viability without the need of long-term immune-modulation.

Vascularized Composite Hand Allograft Procurement and Preparation for Distal and Proximal Forearm Allotransplantation: A Stepwise Approach

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2025

Here, we present a protocol for procuring and preparing vascularized composite hand allografts during distal or proximal forearm transplantation.

Surgical Approach to Full Soft Tissue Face Allograft Procurement for Vascularized Composite Allotransplantation

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2025

This protocol details the surgical technique used to harvest and prepare a full-face allograft for transplantation in patients with severe facial disfigurements, focusing primarily on soft tissue procurement with limited bony harvest restricted to the nasal framework.

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