Flow Loop Simulation

Flow loop simulation is a laboratory method that recreates fluid movement through a controlled circuit to study how medical devices and physiological systems respond to flow. A pump drives a fluid through tubing, reservoirs, and a test section while adjustable resistance, pressure, and flow sensors reproduce selected hemodynamic conditions and quantify device performance. In medicine, this approach supports evaluation of blood pumps, catheters, vascular grafts, and other flow-dependent technologies before clinical use. By enabling repeatable testing without immediate reliance on patients, flow loop simulation helps identify design limitations, compare devices, and improve understanding of fluid dynamics relevant to safety and treatment outcomes.

Flow Loop Simulation - Related Videos

Research

JoVE Journal - Engineering

Visualizing Hyporheic Flow Through Bedforms Using Dye Experiments and Simulation

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Cited by 4 •

2015

This manuscript describes how to create regular bedforms in a flume, visualize flow through the bedforms, and use computer simulations to simulate the hyporheic flow. The computer simulations compare well with the experimental observations. This coupled simulation and experiment is well-suited for both research and educational purposes.

Education

JoVE Science Education - Engineering

Computational Fluid Dynamics Simulations of Blood Flow in a Cerebral Aneurysm

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2023

Source: Joseph C. Muskat, Vitaliy L. Rayz, and Craig J. Goergen, Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana The objective of this video is to describe recent advancements of computational fluid dynamic (CFD) simulations based on patient- or animal-specific vasculature. Here, subject-based vessel segmentations were created, and, using a combination of open-source and commercial tools, a high-resolution numerical solution was determined within a flow model.

Chemical Gardens as Flow-through Reactors Simulating Natural Hydrothermal Systems

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Cited by 30 •

2015

We describe chemical garden formation via injection experiments that allow for laboratory simulations of natural chemical garden systems that form at submarine hydrothermal vents.

Catheterization of Intestinal Loops in Ruminants

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Cited by 4 •

2009

We describe a novel surgical method for catheterizing 'intestinal loops' within the ileum of sheep. Once animals have recovered from surgery and have cleared antibiotics and analgesics, multiple treatments can be deposited directly in loops via the catheters.

Research

JoVE Journal - Neuroscience
Free Sample

MPI CyberMotion Simulator: Implementation of a Novel Motion Simulator to Investigate Multisensory Path Integration in Three Dimensions

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Cited by 48 •

2012

An efficient way to gain insight into how humans navigate themselves in three dimensions is described. The method takes advantage of a motion simulator capable of moving observers in ways unattainable by traditional simulators. Results confirm that movement in the horizontal plane is underestimated, while vertical movement is overestimated.

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