Intracardiac Embolism

Intracardiac embolism is the formation or lodging of an embolic mass within the heart, a clinically important condition because it can obstruct blood flow or travel to vital organs. Emboli most often arise from thrombi formed when blood stasis, endothelial injury, or hypercoagulability promotes clot formation in a cardiac chamber; movement through the pulmonary or systemic circulation depends on its origin and pathway, including possible passage through a septal defect. In medicine, echocardiography and other imaging methods help identify intracardiac thrombi and guide anticoagulation, thrombolysis, or surgical and catheter-based removal. Early recognition can reduce stroke, pulmonary embolism, and hemodynamic compromise.

Intracardiac Embolism - Related Videos

Research

JoVE Journal - Medicine

Combination of High Ligation and Intraoperative Embolization Using Polidocanol for Treatment of Varicoceles

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2023

To reduce the postoperative recurrence rate of varicocelectomy, we combined high ligation of varicocele with intraoperative embolization. We injected polidocanol from the spermatic vein during surgery to embolize the branches of the spermatic vein and collateral veins. This is an alternative surgical method for the treatment of varicocele.

Research

JoVE Journal - Neuroscience
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Microvascular Embolism Mouse Model for In Vivo Two-photon Microscopy Using Fluorescent Polystyrene Microspheres

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2025

This protocol contains a thorough description of a step-by-step approach for a chronic cranial window and microvascular embolism mouse model optimized for in vivo two-photon microscopy imaging using fluorescent polystyrene microspheres.

Education

JoVE Core - Medical-Surgical Nursing

Pulmonary Embolism I: Introduction

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2025

Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...

Pulmonary Embolism I: Introduction

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2026

A blood clot, or thrombus, is a semi-solid mass composed of fibrin, platelets, and red blood cells. When it forms within a vessel, it can obstruct blood flow, known as thrombosis. If part of the clot detaches, it becomes an embolus that can travel and block distant vessels. When this occurs in the pulmonary arteries, it causes a condition known as pulmonary embolism (PE).Origin and ImpactMost often, the embolus originates from a thrombus in the deep veins of the lower limbs, a condition called...

Ultrasound Imaging-guided Intracardiac Injection to Develop a Mouse Model of Breast Cancer Brain Metastases Followed by Longitudinal MRI

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Cited by 26 •

2014

A breast cancer brain metastasis mouse model is established with ultrasound imaging-guided intracardiac injection of MDA-MB231/Br-GFP cells. Development of multifocal intracranial metastases has been monitored longitudinally using high-resolution 9.4 T MRI.

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