Mouse Organs

Mouse organs are specialized structures that perform essential physiological functions in mice, making them valuable subjects for studying normal biology and disease. Each organ contains organized tissues and cells that coordinate processes such as circulation, metabolism, immunity, filtration, and neural signaling, while genetic and anatomical similarities to humans support controlled biomedical investigation. In medicine, researchers examine mouse organs through histology, imaging, molecular analysis, and tissue collection to model disease, assess drug responses, and investigate mechanisms of injury and repair. These studies help connect cellular changes with whole-organ function and guide the development of diagnostics, therapies, and genetically engineered disease models.

Mouse Organs - Related Videos

Research

JoVE Journal - Chemistry

High Precision Zinc Isotopic Measurements Applied to Mouse Organs

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Cited by 28 •

2015

We present the technique to measure with high precision zinc isotope ratios in mouse organs.

Preparation of Mouse Vomeronasal Organ for Vibratome Sectioning

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2025

This video outlines the isolation of a mouse vomeronasal organ (VNO) and tissue preparation for vibratome sectioning. Sections are used to characterize the biophysical and physiological attributes of a specific group of sensory neurons.

A Focus-Forming Assay for Quantifying Virus Titers in the Organs of an Infected Mouse

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2025

The video demonstrates a procedure for quantifying the Zika virus in multiple mouse organs via a focus-forming assay. The process involves infecting mammalian cell monolayers with virus-infected tissue homogenates, followed by the use of methyl cellulose to prevent viral spread. Subsequently, immunostaining is employed to enable precise quantification and measurement of organ-specific infectivity.

Organ Culture and Whole Mount Immunofluorescence Staining of Mouse Wolffian Ducts

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Cited by 4 •

2017

We present a method for isolation and culture of the mouse Wolffian duct (WD). We also demonstrate a detailed procedure for whole mount immunostaining of cultured/freshly isolated WDs with fluorescently tagged antibodies. Together, these techniques enable the study of WD development, coiling, and differentiation.

Isolation and Characterization of Mouse Antral Oocytes Based on Nucleolar Chromatin Organization

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Cited by 17 •

2016

Here we present a protocol for the characterization of mouse antral oocytes based on nucleolar organization.

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