Ocular Distension Measurement

Ocular Distension Measurement is the quantitative assessment of how the eye and its tissues deform in response to changes in pressure or applied force, providing insight into ocular biomechanics. The process compares ocular shape, dimensions, or movement before and after a controlled stimulus, using imaging or pressure-based recordings to estimate tissue distensibility and resistance to deformation. In medicine, these measurements support evaluation of eye structure and mechanical behavior, helping researchers investigate conditions in which pressure regulation or tissue compliance changes. They also provide a basis for comparing disease progression, treatment effects, and responses to controlled experimental conditions.

Ocular Distension Measurement - Related Videos

Research

JoVE Journal - Medicine

In Vivo Luminal Measurement of Distension-Evoked Urothelial ATP Release in Rodents

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Cited by 1 •

2022

This protocol describes the procedure for measuring ATP concentrations in the lumen of the bladder in an anesthetized rodent.

Research

JoVE Journal - Medicine
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Experimental Glaucoma Induced by Ocular Injection of Magnetic Microspheres

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Cited by 25 •

2015

We present a method for inducing elevated intraocular pressure (IOP), by injecting magnetic microspheres into the rat eye, to model glaucoma. This leads to strong pressure rises, and extensive neuronal death. This protocol is easy to perform, does not require repeat injections, and produces stable long-lasting IOP rises.

Measurement of Pulse Propagation Velocity, Distensibility and Strain in an Abdominal Aortic Aneurysm Mouse Model

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Cited by 10 •

2020

This manuscript describes a detailed protocol for using high frequency ultrasound imaging to measure luminal diameter, pulse propagation velocity, distensibility and radial strain on a mouse model of abdominal aortic aneurysm.

A Method to Induce Ocular Surface Inflammation in a Murine Model

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2025

This video demonstrates a method to induce ocular surface inflammation and meibomian gland dysfunction in a murine model. Stimulation of the mouse's immune system using an immunogen and later restimulation with the same immunogen promotes ocular surface inflammation, which causes plugging of meibomian gland secretion through neutrophil-produced aggNETs and leads to dry eye disease.

Ocular Kinematics Measured by In Vitro Stimulation of the Cranial Nerves in the Turtle

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2018

This protocol describes how to use an in vitro isolated turtle head preparation to measure the kinematics of their eye movements. After removal of the brain from the cranium, cranial nerves can be stimulated with currents to quantify rotations of the eye and changes in pupil sizes.

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