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JoVE Journal
Medicine

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Experimental Glaucoma Induced by Ocular Injection of Magnetic Microspheres
 

Experimental Glaucoma Induced by Ocular Injection of Magnetic Microspheres

Article DOI: 10.3791/52400
February 2nd, 2015

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Summary February 2nd, 2015

We present a method for inducing elevated intraocular pressure (IOP), by injecting magnetic microspheres into the rat eye, to model glaucoma. This leads to strong pressure rises, and extensive neuronal death. This protocol is easy to perform, does not require repeat injections, and produces stable long-lasting IOP rises.

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