Organ Recovery
Organ Recovery - Related Videos
09:50
Electrochemically and Bioelectrochemically Induced Ammonium Recovery
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Cited by 31 •
2015
We demonstrate the extraction of ammonium from an ammonium-rich stream using an electrochemical and a bioelectrochemical system. The reactor setup, operation and data analysis are discussed.
03:59
Preparation of Brain Sections Using a NMDG-Based Protective Recovery Method
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2025
This video describes a protocol to obtain brain slices using an N-Methyl-D-glucamine (NMDG)-based protective recovery method. A dissected brain is incubated in an aCSF with NMDG and HEPES to minimize neuronal cell death and damage during the sectioning. The section is allowed to recover in the aCSF to restore the cellular...
08:54
Functional Human Liver Preservation and Recovery by Means of Subnormothermic Machine Perfusion
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Cited by 29 •
2015
We describe a method of ex vivo machine perfusion of human liver grafts at subnormothermic temperature (21 °C).
03:02
Organic Compounds
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2020
All living things are formed mostly of carbon compounds called organic compounds. The category of organic compounds includes both natural and synthetic compounds that contain carbon. Although a single, precise definition has yet to be identified by the chemistry community, most agree that a defining trait of organic molecules is the presence of carbon as the principal element, bonded to hydrogen and other carbon atoms. However, some carbon-containing compounds such as carbonates, cyanides, and...
01:24
Muscle Recovery and Fatigue
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2024
Muscle fatigue refers to the decline in a muscle's ability to maintain the force of contraction after prolonged activity. It primarily stems from changes within muscle fibers. Even before experiencing muscle fatigue, one may feel tired and have the urge to stop the activity. This response, known as central fatigue, occurs due to changes in the central nervous system, namely the brain and spinal cord. While there is no single mechanism that induces fatigue, it may serve as a protective response...
FAQs
Once blood supply is interrupted, the organ becomes vulnerable to metabolic stress, cellular damage, and loss of function. Cooling and preservation solutions help reduce metabolic activity during this vulnerable interval, while controlled storage or ex vivo perfusion helps maintain protective conditions. Limiting ischemic injury is therefore important because preserved structure and function influence whether an organ remains suitable for transplantation.
The solution is flushed through the organ after surgical removal to support preservation during the period before implantation. Cooling reduces the organ’s metabolic demands, while the preservation environment helps limit cellular damage associated with interrupted circulation. This step prepares the organ for controlled storage or ex vivo perfusion and supports later evaluation of its condition.
Ex vivo perfusion provides an alternative to maintaining an organ only in controlled storage. It keeps the recovered organ in a managed environment outside the body, helping preserve its condition while clinicians evaluate it. The approach may also support rehabilitation of organs that initially show signs of injury, potentially allowing some donated organs to be considered for transplantation.
Suitability depends on how well the organ’s structure and function are maintained during procurement, preservation, transport, and evaluation. Cold preservation, controlled storage, or ex vivo perfusion can reduce damage during these stages, but the organ still requires assessment before implantation. This evaluation helps determine whether preservation has adequately protected the organ for transplantation.
The workflow begins with surgical procurement, followed by flushing the organ with a cold preservation solution. Clinicians then maintain it through controlled storage or ex vivo perfusion during transport and evaluation. Before implantation, the organ is assessed for preserved structure and function. Each stage is intended to limit injury and maintain the organ’s potential for successful transplantation.
Clinicians may use ex vivo perfusion when an organ requires continued controlled maintenance and evaluation outside the body. The method is especially relevant when an organ initially shows signs of injury, because it may provide an opportunity for rehabilitation while its condition is assessed. This can help determine whether the organ remains appropriate for transplantation.
Effective recovery can increase the number of organs available for transplantation by protecting donated organs during procurement, transport, and evaluation. Ex vivo perfusion may further assist with assessing and rehabilitating organs that initially appear injured. If preserved structure and function are maintained or improved sufficiently, organs that might otherwise be excluded may become potential candidates for implantation.
In medicine, recovery connects organ donation with the practical requirements of transplantation. The process protects organ structure and function between removal and implantation, while preservation and evaluation help clinicians make informed decisions about use. By supporting successful transplantation and enabling assessment of injured organs, recovery contributes to better use of donated organs and broader access to transplantable tissue.